Medindia » Consumer Health » Medication Manual » Trandolapril

Trandolapril

Latest prescription information about Trandolapril. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
Email Email Save this page Save Syndicate Syndicate
Generic Name : Trandolapril
Pronunciation : tran dole' a pril
Trade Name(s): 
India- Zetpril.
International- Mavik, Zetpril Tab.
Why it is prescribed (Indications) : 
This medication is an angiotensin-converting enzyme (ACE) inhibitor, prescribed for high blood pressure either alone or with other medications. Lowering high blood pressure helps prevent strokes, heart attacks and kidney problems. This medication is also used to improve survival after an acute heart attack and with other drugs (e.g., diuretics, digoxin) to treat congestive heart failure.

When it is not to be taken (Contraindications): 


Hypersensitivity, last 6 months of pregnancy.

Pregnancy Category :

A B C D X
Category D : There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.


When it is to be taken : 
PO- Hypertension- Adult: Initially, 0.5 mg once daily. First dose preferably given at bedtime. Maintenance: 1-2 mg once daily. Max: 4 mg daily in 1-2 divided doses.
In patients with co-existing heart failure, start treatment under close medical supervision.
PO- Heart failure after a heart attack- Adult: Initially, 0.5 mg once daily, may increase dose gradually to a target dose of 4 mg once daily. Patient may continue at the max tolerated dose if patient is unable to tolerate 4 mg/day dose.
How it should be taken : 
It comes as a tablet to take by mouth (orally), once or twice a day with or with out food.
Special Instruction : 
*Caution should be exercised in patients with history of kidney disease, liver disease, high blood levels of potassium, heart problems, severe dehydration ,diabetes, strokes, autoimmune diseases, pregnancy and breastfeeding.
*Drink adequate fluids to prevent from becoming dehydrated.
*It may cause dizziness, lightheadedness, or fainting; alcohol, hot weather, exercise, or fever may increase these effects. Get up slowly from bed.
*It may lead to development of a serious adverse effect in which the patient experiences rapid swelling of the hands, face, lips, eyes, throat, or tongue; difficulty swallowing or breathing; or unusual hoarseness .
Side Effects : 
Heart- Low blood pressure, slow heart rate, poor blood supply, intermittent claudication ( reduced blood flow to the legs, stroke).
Central Nervous System- Dizziness, lightheadedness, loss of consciousness.
Gastrointestinal- Stomach upset, diarrhea.

Metabolic- Increase in potassium, decrease in calcium in blood.
Musculoskeletal- Muscle pain.
Respiratory- Cough.
Miscellaneous- Anaphylactoid reactions (allergic reaction include: rash, itching, swelling (especially of the face, lips, tongue, or throat), trouble breathing.
Other Precautions : 
*It may increase blood sugar; diabetes patients should monitor their blood glucose level regularly.
Storage Conditions : 
Keep this medication in an airtight container, and away from children. Store it at room temperature.

Comment & Contribute
Comments should be on the topic and should not be abusive. Comments are normally moderated and are reviewed after they are posted.
* Your comment can be maximum of 2500 characters
I agree to the terms and conditions
If you have a question about health related issues, you can now post it in our Ask An Expert section on our community website Medwonders.com and get answers from our panel of experts.

Browse the Drugs alphabetically

Drugs Index
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Price List