Generic Name : Tositumomab and Iodine 1131 Tositumomab Pronunciation : tos-IT-too-moe-mab Therapeutic Classification : Radioactive Monoclonal Antibody
International- Bexxar. Why it is prescribed (Indications) :
This medication is a monoclonal antibody, prescribed for non-Hodgkin lymphoma. When it is not to be taken (Contraindications):
Contraindicated to pregnant women.
Dosage & When it is to be taken :
The recommended dose is 450 mg intravenously in 50 ml 0.9% Sodium Chloride over 60 minutes. How it should be taken :
It comes as a solution for injection to be administered by a healthcare provider into the vein. Warnings and Precautions :
* Caution should be exercised in patients with history of infection, thyroid problems, recent vaccination, who are taking other medications, during pregnancy and breastfeeding.
* It may cause dizziness or drowsiness, do not drive a car or operate machinery while taking this medication.
* Avoid live vaccination during the treatment period.
* Monitor complete blood cell counts, platelet counts, thyroid function tests, and kidney function tests regularly while taking this medication. Side Effects :
General- Weakness, fever, infection, pain, chills, headache, abdominal pain, back pain, chest pain, neck pain.
Heart - Low blood pressure, dilatation of blood vessels.
Gastrointestinal - Nausea, vomiting, loss of appetite, diarrhea, constipation, and indigestion.
Metabolic - Underactive thyroid, swelling in the extremities, weight loss.
Musculoskeletal - Muscle pain, joint pain.
Central Nervous System - Dizziness and drowsiness.
Respiratory - Increased cough, inflammation of pharynx, difficulty in breathing, pneumonia.
Skin - Rash, itching, increased sweating.
* Avoid excess dosage. Storage Conditions :
Store it in refrigerator (2°–8°C).
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