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Generic Name : Tositumomab and Iodine 1131 Tositumomab
Pronunciation : tos-IT-too-moe-mab
Therapeutic Classification : Radioactive Monoclonal Antibody
Trade Name(s): International- Bexxar. Why it is prescribed (Indications) : This medication is a monoclonal antibody, prescribed for non-Hodgkin lymphoma. When it is not to be taken (Contraindications): Contraindicated to pregnant women.
Dosage & When it is to be taken : The recommended dose is 450 mg intravenously in 50 ml 0.9% Sodium Chloride over 60 minutes. How it should be taken : It comes as a solution for injection to be administered by a healthcare provider into the vein. Warnings and Precautions : * Caution should be exercised in patients with history of infection, thyroid problems, recent vaccination, who are taking other medications, during pregnancy and breastfeeding. * It may cause dizziness or drowsiness, do not drive a car or operate machinery while taking this medication. * Avoid live vaccination during the treatment period. * Monitor complete blood cell counts, platelet counts, thyroid function tests, and kidney function tests regularly while taking this medication. Side Effects : General- Weakness, fever, infection, pain, chills, headache, abdominal pain, back pain, chest pain, neck pain. Heart - Low blood pressure, dilatation of blood vessels. Gastrointestinal - Nausea, vomiting, loss of appetite, diarrhea, constipation, and indigestion. Metabolic - Underactive thyroid, swelling in the extremities, weight loss. Musculoskeletal - Muscle pain, joint pain. Central Nervous System - Dizziness and drowsiness. Respiratory - Increased cough, inflammation of pharynx, difficulty in breathing, pneumonia. Skin - Rash, itching, increased sweating. * Avoid excess dosage. Storage Conditions : Store it in refrigerator (2°–8°C). |
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