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Topotecan
Latest prescription information about Topotecan. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
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Generic Name : Topotecan
Pronunciation : toe'' poe tee' kan
Therapeutic Classification : Chemotherapy
Trade Name(s):
India- Cantop Vial, Topotel 4 Vial, Topotel Inj. International-Hycamtin. This medication is a topoisomerase type I inhibitor, prescribed for ovarian or lung cancer that do not respond well to other types of cancer treatment. It kills the cancer cells in ovary and in lungs. When it is not to be taken (Contraindications):
When it is to be taken : IV- The recommended dose is 1.5 mg/m2/day over 30 minutes, on 1 to 5 days. It is given in uterus and small cell lung cancer as an IV infusion in a dose of 1.5 mg/m2/day for the first 5 days of a 21-day course. The patient has to undergo at least 4 courses. In cancer of the cervix a dose of 0.75 mg/m2 is given for 3 days along with cisplatin on the first day of a 21-day course. How it should be taken : This medication available in the form of capsule to take by mouth with a full glass (8 ounces) of water, with or without food. (Swallow whole, do not open/ chew/ crush.) Injection: Intravenously (into a vein) over 30 minutes by healthcare providers. Special Instruction : *Caution needed for patients with history of pre existing bone marrow depression. *Frequent monitoring of blood counts during treatment. *It may cause dizziness, do not drive a car or operate machinery while taking this medication. Side Effects : Central Nervous System- Fatigue, weakness, discomfort,headache. Blood- Abnormal low white blood cell count, hemoglobin. Miscellaneous- GI upset, total hair loss, shortness of breath, itching and increased levels of bilirubin. *Avoid alcoholic beverages while taking this medication. Storage Conditions : Intravenous: Unopened vial: Store at 20-25°C; protect from light. Reconstituted solution: Stable for 24 hour at 20-25°C in ambient light. |
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