Information about Tolvaptan

Generic Name : Tolvaptan
Up-to-date prescription details regarding Tolvaptan are provided here.

Pronunciation : tol-VAP-tan

Learn the correct pronunciation of the Tolvaptan, understand it's uses, recommended dosages, its indications, how to take, when to take, when not to take, side effects, special precautions, warnings and its and its storage instructions.

You will also find a list of the medication's International and Indian brand or trade names, as well as its pricing information. For verification of the information presented on this page or for additional clarifications, it's advisable to consult your doctor.

Trade Names/Brand Names of Tolvaptan

Tolvamac (30mg) | Tolvamac (15mg) | Vaptan

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International :

Samsca

Why is Tolvaptan Prescribed? (Indications)

Tolvaptan is a selective vasopressin V2-receptor antagonist, prescribed for hyponatremia (low blood sodium levels).
It works by increasing fluid excretion from the body.

When should Tolvaptan not be taken? (Contraindications)

Hypersensitivity.

What is the dosage of Tolvaptan?

PO- The usual starting dose is 15 mg administered once daily. Increase up 30 mg once daily. Maximum: 60 mg once daily.

How should Tolvaptan be taken?

It comes as a tablet to take by mouth, with or without food.

What are the warnings and precautions for Tolvaptan?

• Cautions should be exercised in patients with history of diabetes, kidney disease, liver disease, use/abuse of alcohol, who are taking other medications, any allergy, during pregnancy and breastfeeding.

• Avoid becoming dehydrated; drink adequate fluids.

• It may raise blood sugar level; if it is so consult with your doctor.

♦Patient may develop with increased risk of Osmotic demyelination syndrome.

What are the side effects of Tolvaptan?

Most Common - Increased thirst, dry mouth, weakness, constipation, increased urination and increased blood sugar.
Blood - Blood clot events.
Heart - Severely abnormal heart rhythm, prolonged prothrombin time.
Gastrointestinal - Intestinal inflammation.
Metabolic - Diabetic ketoacidosis.
Musculoskeletal - Rhabdomyolysis.
Central Nervous System - Stroke.
Genitourinary - Urethral bleeding, vaginal bleeding.
Respiratory - Blood clot in lungs, respiratory failure.
Vascular disorder - Deep vein thrombosis.