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Tolbutamide

Latest prescription information about Tolbutamide. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
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Generic Name : Tolbutamide
Pronunciation : tole byoo' ta mide
Therapeutic Classification : antidiabetics
Trade Name(s): 
India- Rastinone, Tolbutamide.
International- Diabinese, Orinase, Tolinase, Apo-Tolbutamide, Artosin, Diaval, Mobenol, Novo-Butamide, Rastinon.
Why it is prescribed (Indications) : 
This medication is an antidiabetic agent, prescribed for type 2 diabetes.

When it is not to be taken (Contraindications): 


Contraindicated in patients with diabetes, severe burn and hypersensitivity.

Pregnancy Category :

A B C D X
Category C : Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.


When it is to be taken : 
PO- The recommended dose range is 0.5 to 3 grams daily.
How it should be taken : It comes as a tablet to take by mouth, with food.
Special Instruction : 
* Caution should be exercised in patients with history of liver, kidney, thyroid, or heart problems, stomach problem, alcoholism, any allergy, who are taking other medications, during pregnancy and breastfeeding.
* It may cause drowsiness, dizziness, blurred vision, or lightheadedness, do not drive a car or operate machinery while taking this medication.
* Avoid alcohol consumption.
* It may affect blood sugar level; monitor sugar level regularly.
* Avoid exposure to sunlight.
* It should not be used in children.
Side Effects : 
Most Common - Feeling of stomach fullness, heartburn, nausea and decrease in blood sugar level.
Gastrointestinal - Jaundice, nausea and heartburn.
Skin - Allergic skin reactions such as itching, redness, hives, sensitivity to light and bruising.
Blood - Decrease in white/red blood cells, platelets and anemia.
Miscellaneous - Weakness, fatigue, dizziness, vertigo, malaise and headache are reported very rarely.
Other Precautions : 
* Avoid excess dosage.
Storage Conditions : 
Store it at room temperature.

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