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Tolazamide

Latest prescription information about Tolazamide. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
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Generic Name : Tolazamide
Pronunciation : tole az' a mide
Therapeutic Classification : Antidiabetics
ICD Code : Y42.3
Trade Name(s): 
International- Tolinase.
Why it is prescribed (Indications) : 
This medication is a sulfonylurea antidiabetic, prescribed for type 2 diabetes either alone or with other medications.  
When it is not to be taken (Contraindications): 
Contraindicated in patients with diabetes, severe burns and hypersensitivity.

Pregnancy Category :

A B C D X
Category C : Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

Dosage & When it is to be taken : 
The recommended initial dose is 100 mg to 250 mg orally daily with breakfast.
How it should be taken : 
It comes as a tablet to take by mouth, with food.
Warnings and Precautions : 
* Caution should be exercised in patients with history of liver, kidney, thyroid or heart problems, stomach problem, alcoholism, any allergy, who are taking other medications, during pregnancy and breastfeeding.
* It may cause drowsiness, dizziness, blurred vision or lightheadedness, do not drive a car or operate machinery while taking this medication.
* Avoid alcohol consumption.
* It may affect blood sugar level; monitor sugar level regularly.
* Avoid exposure to sunlight.
* It should not be used in children.
Side Effects : 
Most Common - Decrease in blood sugar level.
Gastrointestinal - Jaundice, nausea, epigastric fullness and heartburn.
Skin - Allergic skin reactions such as itching, redness, hives, sensitivity to light and bruising.
Blood - Decrease in white/red blood cells, platelets and anemia.
Miscellaneous - Weakness, fatigue, dizziness, vertigo, malaise and headache reported very rarely.
Other Precautions : 
* Avoid excess dosage.
Storage Conditions : 
Keep this medication in an airtight container and away from children.
Store it at room temperature.

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Reference  

  • Food and Drug Administration (FDA)
  • National Institutes of Health (NIH)
  • PubMed
  • CIMS
  • Indian Pharma Reference Guide 2012
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