Generic Name : Tirofiban Hcl Pronunciation : tye-roe-FYE-ban Therapeutic Classification : Anticoagulants / Antithrombotics ICD Code : Y44.2
India- Aggramed, Aggrastat, Aggribloc, Aggritor, Agraban, GP-2 Ban, Tiroban, Tirofuse, Xtrabaniv.
International- Aggrastat. Why it is prescribed (Indications) :
This medication is a platelet aggregation inhibitor, prescribed for the management of patients with unstable angina or non-Q-wave myocardial infarction, including patients who may subsequently undergo percutaneous transluminal coronary angioplasty (PTCA) with other medications. When it is not to be taken (Contraindications):
Contraindicated in patients with active internal bleeding, stroke, brain tumor, aneurysm, trauma, high blood pressure, and hypersensitivity.
Dosage & When it is to be taken :
Adult: IV- Non-ST-segment elevation MI; Unstable angina- Loading dose: 0.4 mcg/kg/min for 30 mins, then 0.1 mcg/kg/min for ≥24-48 hours. How it should be taken :
It comes as a solution for injection to be administered by a healthcare provider into the vein. Warnings and Precautions :
* Caution should be exercised in patients with history of decreased blood platelets, high blood volume, kidney impairment, bleeding problems in the eye, any allergy, who are taking other medications, elderly, children, during pregnancy and breastfeeding.
* It may cause dizziness, do not drive a car or operate machinery while taking this medication.
* It may reduce platelet counts; avoid injury or bruising to prevent bleeding.
* Monitor complete blood counts regularly while taking this medication. Side Effects :
Most Common - Major bleeding.
Body as a Whole - Fever and chills.
Central Nervous System - Dizziness.
Skin - Sweating.
Musculoskeletal - Leg pain.
Heart - Slow heart beat.
* Avoid excess dosage. Storage Conditions :
Store it at room temperature (25°C).
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