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Ticlopidine

Latest prescription information about Ticlopidine. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
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Generic Name : Ticlopidine
Pronunciation : tye kloe' pi deen
Therapeutic Classification : Anticoagulants / Antithrombotics
ICD Code : Y44.2
Trade Name(s): 
India- Aplaket Tab, Tic Tab, Ticlantin Tab, Ticlobest Tab, Ticlop Tab , Ticlopid Tab, Ticlovas Tab, Tikla Tab, Tikleen Tab, Tilkon Tab, Tyklid Tab.
International- Ticlid.
Why it is prescribed (Indications) : 
This medication is a platelet aggregation inhibitor, prescribed for reducing the risk of thrombotic stroke. It works by thinning the blood that helps to reduce the risk of blood clots.
When it is not to be taken (Contraindications): Contraindicated in patients with blood disorder, intracranial bleeding, stomach bleeding, liver impairment and hypersensitivity.

Pregnancy Category :

A B C D X
Category B : Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.

Dosage & When it is to be taken : 
PO- The recommended dose is 250 mg two times per day taken with food.
How it should be taken : 
It comes as a tablet to take by mouth, with food.
Warnings and Precautions : 
* Caution should be exercised in patients with history of blood or immune disorders, liver or kidney problems, bleeding/blood clotting disorders, high cholesterol or triglyceride levels, elderly, children, during pregnancy and breastfeeding.
* It may cause dizziness or drowsiness, do not drive a car or operate machinery while taking this medication.
* Avoid alcohol consumption.
Side Effects : 
Most Common- Diarrhea, rash, nausea, vomiting, GI pain and decrease in neutrophils.
Miscellaneous- Loss of appetite, bruising, flatulence, itching and abnormal liver function.
Other Precautions : 
*Avoid excess dosage.
Storage Conditions : 
Store it at controlled room temperature (15° to 30°C) and in an airtight container.

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Reference  

  • Food and Drug Administration (FDA)
  • National Institutes of Health (NIH)
  • PubMed
  • CIMS
  • Indian Pharma Reference Guide 2012
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