Tibolone - Drug InformationGeneric Name : Tibolone | Pronunciation : ti-bo-lone
International :Tibofem, Boltin, Climafem, Climatix, Clitax, Discretal, Femenil A, Femsel, Fomene, Goldar, Heria, Ladybon, Libiam, Lirex, Livial, Liviel, Liviella, Livifem, Menorest, Menotibol, Menotrix, Neotilom, Paraclim, Pauxa, Plenovid, Reduclim, Senalina, Tibelox, Tiboclim, Tibofem, Tibogyn, Tibolon Zentiva, Tibolona Teva, Tibolona, Tibolone Teva, Tibolux, Tibone, Tibonella, Tiboteva, Tinox, Tirovarina, Tobe, Tocline, Ubilon, Xyvion
Why it is prescribed (Indications) :
This medication is a synthetic steroid hormone, prescribed for postmenopausal osteoporosis.
When it is not to be taken (Contraindications):
Contraindicated in patients with breast cancer, undiagnosed vaginal bleeding, severe liver disease, heart disease and hypersensitivity.
Pregnancy Category :
Category D :There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
Dosage & When it is to be taken :
Adult- PO- The recommended dose is 2.5 mg/day.
How it should be taken :
It comes as a tablet to take by mouth, with or without food.
Warnings and Precautions :Caution should be exercised in patients with history of blood clot problems, high cholesterol level, high blood pressure, gall stone, uterine fibroids, liver, kidney diseases, severe vaginal bleeding, sugar, epilepsy, migraine, any allergy, who are taking other medications, during pregnancy and breastfeeding.
It should not be used in women within one year of menopause because of irregular periods.
It may affect blood sugar level; dose adjustment needed for anti-diabetic medications.
Patient may experience with high blood pressure, abnormal liver function, bleeding problem; if it is so consult with your doctor.
Side Effects :
Most Common - Weight changes, swelling in the ankle, dizziness, headache and depression.
Genitourinary - Irregular vaginal bleeding.
General - Abdominal pain, GI disturbances, muscle pain, hair loss, skin rash and itching.