Generic Name : Thrombin Topical Bovine Origin Pronunciation : THROM-bin Therapeutic Classification : Hematologic Agents
International- Thrombin- JMI, Recothrom, Thrombi-Gel 10, Thrombi-Gel 40, Thrombi-Gel 100, Thrombi-Pad 3×3. Why it is prescribed (Indications) :
This medication is hematologic agent, prescribed for hemostasis and for temporary control of moderately to severely bleeding wounds. When it is not to be taken (Contraindications): Hypersensitivity.
Dosage & When it is to be taken :
Topical- The recommended concentration of 1,000 to 2,000 International Units/mL is required. How it should be taken :
It comes as a solution for topical use; apply as directed by your physician. Warnings and Precautions :
* Caution should be exercised in patients with history of infection, any allergy, elderly, children, during pregnancy and breastfeeding.
* For external use only.
* Patient may develop with increased risk of infections such as Creutzfeldt-Jakob disease; if it is so consult with your healthcare provider. Side Effects :
Most Common - Allergic reactions.
Heart - Blood clots.
Gastrointestinal - Nausea and vomiting.
Lab Tests - Increased APTT, prolonged PT, decreased lymphocytes, increased neutrophils.
Miscellaneous - Incision-site complication, injection site pain, infection, bleeding, postoperative wound infection, itching, and antibody formation.
* Avoid excess dosage. Storage Conditions :
Store it at 2°–25°C.
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