Thiotepa - Drug Information

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General Information on Thiotepa

Generic Name : Thiotepa

Pronunciation : (thye oh tep' a)

Latest prescription information about Thiotepa. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.

Trade Names/Brand Names of Thiotepa

India : 

International : 

Thioplex

Why is Thiotepa Prescribed? (Indications)

This medication is a chemotherapy agent, prescribed for ovary or breast cancer.  It works by killing cancer cells.

When should Thiotepa not to be taken? (Contraindications)

Contraindicated in patients with liver, kidney disease, bone marrow depression and hypersensitivity.

Pregnancy Category

A B C D X

Category D :

There is an evidence of fetal risk based on adverse reaction data, but potential benefits may allow the drug to be used in pregnant women despite risks.

What is the dosage of Thiotepa?

Breast and Ovarian Carcinoma: Adults- IV- 0.3 to 0.4 mg/kg every 1 to 4 week. Alternative regimens- 0.2 mg/kg/day for 4 to 5 days every 2 to 4 week; or 6 mg/m 2 /day for 4 to 5 days every 2 to 4 week.

How should Thiotepa be taken?

It comes as a solution for injection to be administered by a healthcare provider into the vein.

What are the warnings and precautions for Thiotepa?

Caution should be exercised in patients with history of kidney or liver problems, bone marrow problems, agranulocytosis, any allergy, who are taking other medications, during pregnancy and breastfeeding.
It may cause dizziness or blurred vision, do not drive a car or operate machinery while taking this medication.
It may reduce platelet counts, avoid injury or bruising.
Avoid live vaccination.

What are the side effects of Thiotepa?

   General : Fatigue and weakness.
   Hypersensitivity : Allergic reactions - rash, hives, laryngeal edema, asthma, shock and wheezing.
   Local : Skin inflammation and pain at the injection site.
   Gastrointestinal : Nausea, vomiting, abdominal pain and loss of appetite.
   Genitourinary : Painful urination and urinary retention.
   Respiratory : Difficulty in breathing.
   Central Nervous System : Dizziness, headache and blurred vision.
   Skin : Hair loss.
   Eye : Eye inflammation.
   Genitourinary : Absence of menstrual periods and decrease in sperm count.

What are the other precautions for Thiotepa?

Monitor liver function, kidney function, and white blood cell counts regularly while taking this medication.

What are the storage conditions of Thiotepa?

Store it at 8C and in the container it came in.


Schedule : G

Drugs that are to be used only under medical supervision.

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We are one of the leading manufacturers of Pharmaceutical ingredients. You can visit our website at www.glandpharma.com. We currently require Thiotepa API. Please send us your best possible Quote.

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