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Thalidomide

Latest prescription information about Thalidomide. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
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Generic Name : Thalidomide
Pronunciation : tha LID o mide
Therapeutic Classification : Antileprotics
ICD Code : Y41.1
Trade Name(s): 
India- Oncothal, Talimyde, Thaangio, Thalix, Thaloda, Thaloma, Thalon, Thycad.
International- Thalomid.
Why it is prescribed (Indications) : 
This medication is an immunomodulatory agent, prescribed for multiple myeloma, and erythema nodosum leprosum (ENL).  It works on the immune system to decrease certain substances that cause skin inflammation
When it is not to be taken (Contraindications): Contraindicated in pregnant and breastfeeding women, and known hypersensitivity.

Pregnancy Category :

A B C D X
Category X : Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use of the drug in pregnant women clearly outweigh potential benefits.

Dosage & When it is to be taken : 
The recommended dose is 200mg administered orally once daily with water, preferably at bedtime and at least 1-hour after the evening meal.
How it should be taken : 
It comes as a capsule to take by mouth, with food.
Warnings and Precautions : 
* Caution should be exercised in patients with history of human immunodeficiency virus (HIV), acquired immunodeficiency syndrome (AIDS), decrease in white blood cells, seizures, and in children.
* It may cause dizziness or drowsiness, do not drive a car or operate machinery and get up slowly from bed while taking this medication.
* Avoid alcohol consumption while taking this medication.
Side Effects : 
Most Common - Drowsiness, dizziness, constipation, confusion, difficulty in breathing and rash.
Body as a Whole - Abdominal pain, accidental injury, weakness, back pain, chills, swelling in the face, fever, headache, uneasiness and infection.
Gastrointestinal - Loss of appetite, constipation, diarrhea, dry mouth, flatulence, liver function abnormalities, nausea and tooth pain.
Blood - Anemia and decrease in white blood cells.
Metabolic - Swelling in the extremities, increased cholesterol and elevated liver enzyme.
Central Nervous System - Agitation, dizziness, sleeplessness, nervousness, nerve disease, tingling, drowsiness, tremor and unsteadiness.
Respiratory - Inflammation of pharynx/sinus and runny nose.
Skin - Pimples, skin inflammation, nail disorder, itching and increased sweating.
Genitourinary - Blood in urine and impotence.
Other Precautions : 
* Avoid excess dosage.
Storage Conditions : 
Store the medication at 25°C.

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Member Comments ( 1 )
I wish to know that is there any studies for of Thalidomide for the patients of Ankylosing Spondalytis.
(Posted by P.P.Singh, N/A Date : 4/18/2013 )

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Reference  

  • Food and Drug Administration (FDA)
  • National Institutes of Health (NIH)
  • PubMed
  • CIMS
  • Indian Pharma Reference Guide 2012
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