Why it is prescribed :
This medication is angiotensin receptor blocker (ARBs), prescribed for hypertension. It works by relaxing blood vessels.
When it is not to be taken (Contraindications): ♦Contraindicated in patients with known hypersensitivity. It should not be co-administered with aliskiren in patients with diabetes.
Category C :
Animal studies have shown adverse effects on the fetus and there are no appropriate studies in pregnant women, but potential benefits may allow the use of the drug in pregnant women despite the potential for risks.
Dosage & When it is to be taken (Indications):
Hypertension- Adults- Oral: Initial: 40 mg once daily. Max: 80 mg/day.
Cardio Vascular risk reduction- Adults- Oral: 80 mg once per day.
How it should be taken :
It comes as a tablet to take by mouth, with or without food.
Warnings and Precautions :
Caution should be exercised in patients with history of heart, liver or kidney disease, children, during pregnancy and breastfeeding.
It may cause dizziness or drowsiness, do not drive a car or operate machinery while taking this medication.
Avoid alcohol consumption while taking this medication.
Patients may develop with severe allergic reactions; if it so consult with your doctor.
It may cause diarrhea, dehydration, excessive sweating or vomiting which leads to low blood pressure.
Side Effects :
Headache, dizziness and diarrhea.
Body as a Whole
Allergy, fever, leg pain and uneasiness.
Palpitations, chest pain, fast heart rate, leg swelling and abnormal ECG.
Central Nervous System
Sleeplessness, drowsiness, headache, unsteadiness, tingling, involuntary muscle contractions, decreased sensitivity, impotence, increased sweating flushing, anxiety, depression and nervousness.
Flatulence, constipation, stomach inflammation, vomiting, dry mouth, gastro esophageal reflux, tooth pain and nonspecific gastrointestinal disorders.
Increased cholesterol level in blood and sugar.
Joint inflammation/pain and leg cramps.
Fungal infection, abscess and ear inflammation.
Asthma, difficulty in breathing, nosebleed and inflammation of bronchus/nose.
Skin inflammation, rash, redness and itching.
Increased urination frequency and bladder inflammation.
Eye and ENT
Abnormal vision, eye inflammation, ringing in the ear and ear pain.
Other Precautions :
Monitor blood pressure, blood electrolyte levels, heart, kidney or liver function regularly while taking this medication.
Storage Conditions :
Store it at controlled room temperature (15-30°C).
♦ Safety Labeling Changes Approved By FDA