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Telaprevir
Updated on : June - 2012
Latest prescription information about Telaprevir. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
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Generic Name : Telaprevir
Pronunciation : tel-A-pre-vir
Therapeutic Classification : Antivirals
ICD Code : Y41.5
♦ Safety Labeling Changes Approved By FDA
Trade Name(s): International- Incivek. Why it is prescribed (Indications) : This medication is a hepatitis C virus protease inhibitor, prescribed for chronic hepatitis C virus infection with other medications. It decreases the amount of hepatitis C virus (HCV) in the body. When it is not to be taken (Contraindications): Contraindicated in pregnant women, men whose female partners are pregnant, co-administration with drugs that are highly dependent on CYP3A such as alfuzosin, certain benzodiazepines, cabazitaxel, cisapride, conivaptan, dronedarone, ergot derivatives, lurasidone, pimozide, rifabutin, rifampin, rivaroxaban, silodosin, PDE5 inhibitor, St. John's wort, or tolvaptan, and hypersensitivity.
Dosage & When it is to be taken : Adult- PO- The recommended dose is 750 mg (two 375-mg tablets) taken orally 3 times a day. How it should be taken : It comes as a tablet to take by mouth, with food. Warnings and Precautions : * Caution should be exercised in patients with history of HIV infection, gout, blood problems (anemia, low blood platelet levels, or low white blood cell levels), liver impairment, had an organ transplant, any allergy, who are taking other medications, elderly, children, during pregnancy and breastfeeding. * It may reduce platelet counts; avoid injury or bruising. * Avoid contact with people who have infections in order to prevent the spread of infection. * Monitor complete blood cell counts, electrolyte levels, liver and kidney function, hepatitis C virus antibody levels, thyroid function, and uric acid levels regularly while taking this medication. ♦*Patient may develop Stevens Johnson Syndrome (SJS), Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS), and Toxic Epidermal Necrolysis (TEN). Side Effects : Rash, anemia, fatigue, itching, nausea, and vomiting. * Avoid excess dosage. Storage Conditions : Store it at controlled room temperature (25°C). |
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