Tacrolimus - Drug Information

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General Information on Tacrolimus

Generic Name : Tacrolimus

Pronunciation : tak-roe-li-mus

Latest prescription information about Tacrolimus. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
ICD Code : Y43.4 | Therapeutic Classification : Immunosuppressants

Why is Tacrolimus Prescribed? (Indications)

This medication is an immunosupressant, prescribed for preventing organ rejection during transplantation. It decreases the activity of immune system to prevent an organ from rejection. 

When should Tacrolimus not to be taken? (Contraindications)

Hypersensitivity.

Pregnancy Category

A B C D X

Category C :

Animal studies have shown adverse effects on the fetus and there are no appropriate studies in pregnant women, but potential benefits may allow the use of the drug in pregnant women despite the potential for risks.

What is the dosage of Tacrolimus?

Topical- As 0.03% ointment- Apply a thin layer over the affected skin twice daily.

How should Tacrolimus be taken?

It comes as an ointment to apply topically as directed by your physician.

What are the warnings and precautions for Tacrolimus?

Caution should be exercised in patients with heart, kidney or liver disease, any allergy, who are taking other medications, elderly, children, during pregnancy and breastfeeding.
Patient may develop with increased risk of skin cancer; avoid exposure to sunlight.
Wear protective clothing and sunscreen with a high skin protection factor (SPF) to avoid sunburn.
Wear sunglasses avoid eye damage.
It may increase blood pressure; monitor blood pressure level regularly while taking this medication.
Patient may experience with the following symptoms: thirst, excessive hunger, frequent urination, blurred vision and confusion.
Avoid vaccination while taking this medication.

What are the side effects of Tacrolimus?

   Gastrointestinal : Loss of appetite, constipation, dehydration, gastrointestinal disorder, rectal disorder, hernia, intestinal inflammation, mouth ulcer and infection.
   Central Nervous System : Anxiety, dizziness, increased muscle tone, abnormal thinking, uneasiness and headache.
   Heart : Vein inflammation, heart disease, dilatation of blood vessels, fainting, fast heart rate and chest pain.
   Skin : Photosensitivity reaction, skin cancer, skin discoloration, skin overgrowth, skin ulcer, white patches on the skin and sweating.
   Eye and ENT : Abnormal vision, eye swelling, taste perversion, tooth decay, dry eyes, ear disorder, nosebleed and eye pain.
   Respiratory : Difficulty in breathing, lung disorder and inflammation of larynx.
   Metabolic : Increased cholesterol level and over active thyroid.
   Musculoskeletal : Joint inflammation, tendon disorder, nail disorder, neck pain and joint disorder.
   Genitourinary : Unintended pregnancy and vaginal infection/inflammation.
  Blood:Anemia.
   Miscellaneous : Chills, fungal infection and swelling in the extremities.

What are the other precautions for Tacrolimus?

Avoid excess dosage.

What are the storage conditions of Tacrolimus?

Store it at room temperature (25C).

♦ Safety Labeling Changes Approved By FDA

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Elijah 

how can Tacrograf react with Raw Garlic when taking close to one another

cudumbasseri123 

Dear Sir, How can I get TACRIM [tacrolimus] locally. My town is Kozhikode, Kerala. This is for psoriasis Regards, Chandran

nimora 

Hi I'm Ranniel. Please let me know where i can get the medicine called tacrolimus. this is for my daughter who have been liver transplanted. possible to send this by shipment here.

Danya 

Hi My name is Mrs. D. Warnapura.
And iam from Colombo, SriLanka.
My 4yr old daughter was diagnosed with Atopic Dermertitis a few yrs ago...but as of late (from 1 year) it became worse. After consulting with various specialist, i found the best one by the name of Dr. Monica Mohindra M.D. who consults at one of our leading private hospitals in SriLanka. She prescribed this ointment Tacros 0.03% w/w 10gr, to be applyed once daily on the affected area's. I just read ur page wich indicates SEVER side effects....stated above. Pls tell me whether this dose (once daily, in the night) will have a effect on my precious daughter like skin cancer e.c.t.
Because thats the last thing i need to put her through...shes been through enough already. Thanks

SOS...
Danya.

Afzaal Chaudhary 

This site has good information about medicines but should be mentioned the price and location where it is available with telephone nos.

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