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Generic Name : Tacrolimus
Pronunciation : tak-roe-li-mus
Trade Name(s):
India- Acroli Forte Oint, Acroli Oint, Crolim Oint, Crolim Powd Oint, Crolim Tab, Mustopic Oint, Olmis Cap, Olmis Forte Oint, Olmis Oint, Pangraf Cap, Seegraf Tab, Tacel Tube, Tacrel F-Oint, Tacrel Oint, Tacrimus Forte Oint, Tacrimus Oint, Tacroderm Oint, Tacrograf Cap, Tacrokid Oint, Tacromus Cap, Tacrotec Cap, Tacrotor 0.03% Oint, Tacroz F-Oint, Tacroz Forte Oint, Tacroz Oint, Techlomus Oint, Topgraf Oint, Vingraf Cap.
International- Prograf, Protopic.
Why it is prescribed (Indications) :
This medication is an immunosupressant, prescribed for preventing organ rejection during transplantation. It decreases the activity of immune system to prevent an organ from rejection.
When it is not to be taken (Contraindications):
Hypersensitivity.
Category C : Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
When it is to be taken :
Topical- As 0.03% ointment- Apply a thin layer over the affected skin twice daily.
How it should be taken :
It comes as an ointment to apply topically as directed by your physician.
Special Instruction :
* Caution should be exercised in patients with heart, kidney or liver disease, any allergy, who are taking other medications, elderly, children, during pregnancy and breastfeeding.
* Patient may develop with increased risk of skin cancer; avoid exposure to sunlight.
* Wear protective clothing and sunscreen with a high skin protection factor (SPF) to avoid sunburn.
* Wear sunglasses avoid eye damage.
* It may increase blood pressure; monitor blood pressure level regularly while taking this medication.
* Patient may experience with the following symptoms: thirst, excessive hunger, frequent urination, blurred vision and confusion.
* Avoid vaccination while taking this medication.
Side Effects :
Gastrointestinal -
Loss of appetite, constipation, dehydration, gastrointestinal disorder, rectal disorder, hernia, intestinal inflammation, mouth ulcer and infection.
Central Nervous System -
Anxiety, dizziness, increased muscle tone, abnormal thinking, uneasiness and headache.
Heart -
Vein inflammation, heart disease, dilatation of blood vessels, fainting, fast heart rate and chest pain.
Skin -
Photosensitivity reaction, skin cancer, skin discoloration, skin overgrowth, skin ulcer, white patches on the skin and sweating.
Eye and ENT -
Abnormal vision, eye swelling, taste perversion, tooth decay, dry eyes, ear disorder, nosebleed and eye pain.
Respiratory -
Difficulty in breathing, lung disorder and inflammation of larynx.
Metabolic -
Increased cholesterol level and over active thyroid.
Musculoskeletal -
Joint inflammation, tendon disorder, nail disorder, neck pain and joint disorder.
Genitourinary -
Unintended pregnancy and vaginal infection/inflammation.
Miscellaneous -
Chills, fungal infection and swelling in the extremities.
Other Precautions :
*Avoid excess dosage.
Storage Conditions :
Store it at room temperature (25°C).
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