Suramin - Drug InformationGeneric Name : Suramin | Pronunciation : SUR- a- min
International- Germanin, Moranyl, Naganin, Naganine.
Why it is prescribed (Indications) :
This medication is prescribed for sleeping sickness, onchocerciasis (river blindness) and some infections caused by parasites. It works by causing the parasites to lose energy, which causes their death.
When it is not to be taken (Contraindications):Hypersensitivity.
Pregnancy Category :
Category X :Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use of the drug in pregnant women clearly outweigh potential benefits.
Dosage & When it is to be taken :
IV: Dose is based on patientís body weight and response to the medication.
How it should be taken :
It comes as a solution for injection, to be administered by a healthcare provider into the vein.
Warnings and Precautions :Caution should be exercised in patients with history of liver impairment, allergy, decreased serum albumin level,malnutrition, pregnant women, children, elderly and during breastfeeding.
Side Effects :
Central nervous system- Fever, headache, tiredness, fainting, weakness, numbness and increased sensitivity in hand and foot.
Skin- Rash and itching.
Metabolic- Adrenal insufficiency and abnormality in liver enzymes.
Gastrointestinal- Vomiting, abdominal pain, nausea and metallic taste.
Blood- Decrease in blood count.
Liver- Transient increase in bilirubin level.
Musculoskeletal- Tingling and peripheral neuropathy.
Eye- Eye diseases and eye problems.
Genitourinary- Presence of protein in urine and kidney impairment.