Sulfisoxazole - Drug Information

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General Information on Sulfisoxazole

Generic Name : Sulfisoxazole

Pronunciation : sul fi sox' a zole

Latest prescription information about Sulfisoxazole. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
ICD Code : Y41.8 | Therapeutic Classification : Anti- Infectives

Trade Names/Brand Names of Sulfisoxazole

International- Sulfafurazole, Gantrisin.

Why is Sulfisoxazole Prescribed? (Indications)

This medication is a sulfonamide antibacterial, prescribed for treating and preventing certain bacterial infections. It helps keep bacteria from growing in the body.

When should Sulfisoxazole not to be taken? (Contraindications)

Contraindicated in patients with severe kidney disease, anemia, hypersensitivity, during pregnancy and breastfeeding.

Pregnancy Category

A B C D X

Category C :

Animal studies have shown adverse effects on the fetus and there are no appropriate studies in pregnant women, but potential benefits may allow the use of the drug in pregnant women despite the potential for risks.

What is the dosage of Sulfisoxazole?

Initial dose: One half of the 24-hour dose. Maintenance dose: 150 mg/kg/24 hours or 4 gm/Mē/24 hours - dose to be divided into 4 to 6 doses/24 hours.

How should Sulfisoxazole be taken?

It comes as a tablet and liquid to take by mouth, with or without food.

What are the warnings and precautions for Sulfisoxazole?

• Caution should be exercised in patients with history of diarrhea, sore throat, stomach or intestinal infection, asthma, glucose-6-phosphate dehydrogenase (G-6-PD) deficiency, blood problems, liver or kidney problems, any allergy, who are taking other medications.
• It may cause dizziness, do not drive a car or operate machinery while taking this medication.
• Avoid long-term use of this medication; otherwise it may cause secondary infection.
• Avoid exposure to sunlight.
• It should not be used in children less than 2 years old.

What are the side effects of Sulfisoxazole?

•   Allergic Reactions : Shock, serum sickness, rash, hives, itching and sensitivity to light.
•   Heart : Fast heart rate, palpitations, fainting and bluish.
•   Gastrointestinal : Liver inflammation, jaundice, nausea, vomiting, loss of appetite, abdominal pain, diarrhea, gastrointestinal bleeding, blood in stools, flatulence, mouth ulcer, salivary gland enlargement and inflammation of pancreas/tongue.
•   Genitourinary : Blood in urine, BUN and creatinine elevations, kidney inflammation and urinary retention.
•   Blood : Decrease in white blood cells, platelets, bruising, anemia, eosinophilia and clotting disorders.
•   Musculoskeletal : Muscle/joint pain.
•   Central Nervous System : Headache, dizziness, tingling, convulsions, ringing in the ear, unsteadiness, incoordination, stroke, mental depression, hallucinations, disorientation, depression, anxiety and apathy.
•   Respiratory : Cough, shortness of breath and pulmonary infiltrates.
•   Miscellaneous : Swelling in the extremities, fever, drowsiness, weakness, fatigue, lack of energy, rigors, flushing, hearing loss, sleeplessness, lung inflammation and chills.

What are the other precautions for Sulfisoxazole?

Avoid excess dosage.

What are the storage conditions of Sulfisoxazole?

Store it at controlled room temperature (15 to 30°C).

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