Sulfasalazine - Drug Information

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General Information on Sulfasalazine

Generic Name : Sulfasalazine

Pronunciation : sul fa sal' a zeen

Latest prescription information about Sulfasalazine. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
Therapeutic Classification : Miscellaneous Gastrointestinal Products

Trade Names/Brand Names of Sulfasalazine

Why is Sulfasalazine Prescribed? (Indications)

This medication is a salicylate, prescribed for ulcerative colitis. It decreases inflammation.

When should Sulfasalazine not to be taken? (Contraindications)

Contraindicated in patients with blood disorder porphyria, urinary bowel obstruction and hypersensitivity.

Pregnancy Category

A B C D X

Category B :

Animal studies have failed to demonstrate a risk to the fetus and appropriate studies on pregnant women are lacking.

What is the dosage of Sulfasalazine?

Initial Therapy- Adults: 3 to 4 g daily in evenly divided doses with dosage intervals not exceeding eight hours.
Children, six years of age and older: 40 to 60 mg/kg of body weight in each 24-hour period, divided into 3 to 6 doses.

How should Sulfasalazine be taken?

It comes as a tablet to take by mouth, with food.

What are the warnings and precautions for Sulfasalazine?

Caution should be exercised in patients with history of asthma, kidney or liver disease, porphyria, blood problems, or blockage in your intestine or urinary tract, any allergy, who are taking other medications, during pregnancy and breastfeeding.
It may cause drowsiness or dizziness, do not drive a car or operate machinery while taking this medication.
Avoid exposure to sunlight.
Monitor liver function, kidney function, complete blood cell counts, urine tests regularly while taking this medication.
It should not be used in children less than 2 years old.

What are the side effects of Sulfasalazine?

   Most Common : Nausea, indigestion, rash, headache, abdominal pain, vomiting, fever, dizziness, mouth ulcer, itching, abnormal liver function tests, decrease in white blood cells and decrease in platelets.
   Blood : Anemia and bruising.
   Hypersensitivity : Redness of the skin, skin death, shock, hives, hair loss, joint pain, lung inflammation and difficulty in breathing.
   Gastrointestinal : Liver failure, bloody diarrhea, diarrhea, abdominal pain and intestinal inflammation.
   Central Nervous System : Convulsions, sleeplessness, unsteadiness, paralysis, mental depression, unsteadiness, hearing loss, incoordination, hallucinations, ringing in the ear and drowsiness.
   Genitourinary : Absence of urination, kidney inflammation, urinary tract infections, blood in urine and protein in urine.

What are the other precautions for Sulfasalazine?

Avoid excess dosage. Sulfasalazine can cause reduced sperm count in some men which is reversible in 2-3 months after stopping treatment. It also changes the color of the urine and tears making it slightly yellow-orange. Soft Contact lenses may get stained, recommended to use glasses.

What are the storage conditions of Sulfasalazine?

Keep this medication in an container and out of the reach of children.

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Vasudev3 

Is taking 1 g Saaz Ds for AS for a long time is of any help? does the drug have any bad side effects ? If yes how does it surface ? Thanx

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