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Succimer

Latest prescription information about Succimer. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
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Generic Name : Succimer
Pronunciation : SUX-ih-mer
Therapeutic Classification : Chelating Agents
ICD Code : Y57.2
Trade Name(s): 
International- Chemet.
Why it is prescribed (Indications) : 
This medication is a lead chelator, prescribed for the treatment of lead poisoning. It works by trapping lead in the body and removing it in the urine.
When it is not to be taken (Contraindications): Hypersensitivity.

Pregnancy Category :

A B C D X
Category C : Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

Dosage & When it is to be taken : 
Adult- PO- The recommended starting dose is 10 mg/kg or 350 mg/m2 every eight hours for five days.
How it should be taken : 
It comes as a capsule to take by mouth, with or without food.
Warnings and Precautions : 
* Caution should be exercised in patients with history of dehydration, liver or kidney problem, any allergy, who are taking other medications, during pregnancy and breastfeeding.
* It may cause drowsiness or dizziness, do not drive a car or operate machinery while taking this medication.
* Avoid contact with people who have infections.
Side Effects : 
Gastrointestinal - Nausea, vomiting, diarrhea, loss of appetite, loose stools and metallic taste in mouth.
Body as a Whole - Back pain, abdominal cramps, stomach pain, head pain, rib pain, chills, fever, flu-like symptoms and headache.
Metabolic - Increased alkaline phosphatase and serum cholesterol levels.
Central Nervous System - Drowsiness, dizziness, sleepiness and numbness.
Skin - Rash and itching.
Eye and ENT - Watery eyes and inflammation of middle ear.
Respiratory - Sore throat, runny nose, nasal congestion and cough.
Heart - Abnormal heart rhythm.
Other Precautions : 
* Avoid excess dosage.
Storage Conditions : 
Store between 15°C and 25°C and avoid excessive heat.

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Reference  

  • Food and Drug Administration (FDA)
  • National Institutes of Health (NIH)
  • PubMed
  • CIMS
  • Indian Pharma Reference Guide 2012
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