Generic Name : Streptozocin Pronunciation : strep toe zoe' sin
Therapeutic Classification : Chemotherapy Trade Name(s):
International- Zanosar. Why it is prescribed (Indications) :
This medication is an alkylating agent (chemotherapy drug), prescribed for pancreatic cancer. It stops the growth of cancer cells. When it is not to be taken (Contraindications):
Contraindicated in pregnancy and lactation; known hypersensitivity.
Dosage & When it is to be taken :
IV: The recommended dose is 500 mg/day/m2 of body surface area for five consecutive days every six weeks. How it should be taken : It comes as a solution for injection, administered by a healthcare provider into the vein. Warnings and Precautions :
* Caution should be exercised in patients with history of liver or kidney disease and diabetes.
* It may affect menstrual cycle in women, and stop sperm production in men.
* Avoid vaccination while taking this medication.
* It may cause dizziness or drowsiness, do not drive a car or operate machinery while taking this medication.
Side Effects :
Gastrointestinal- Diarrhea, nausea and vomiting.
Liver- Elevated liver enzyme level.
Blood- Decrease in leucocytes and platelet count.
Metabolic- Decrease in sugar level.
Genitourinary- Decreased urination.
Central Nervous System- Dizziness, drowsiness, lightheadedness and weakness.
Skin- Rash and itching.
* Avoid alcoholic beverages.
Storage Conditions :
Store it in refrigerator (2° to 8°C) and protect from light.
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