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Streptokinase

Latest prescription information about Streptokinase. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
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Generic Name : Streptokinase
Pronunciation : strep-toe-KYE-nase
Therapeutic Classification : Enzymes
ICD Code : Y43.6
Trade Name(s): 
India- Cardiostrep Inj, Eskinase Vial, Fibrokinase Vial, Haemokinase Inj, Icikinase Vial, Kabikinase Inj, Myokinase Vial, Niskinase Inj, Prokinase Vial, Shankinase Vial, Stpase Inj Vial, Streplife Vial, Streptase Vial, Streptoken Vial, Streptokinase Vial, Streptonase Vial, Stukinase Inj, Thrombosolv Vial, Zykinase Vial.
International- Streptase.
Overview : Note: This brand is not available in US market.
Why it is prescribed (Indications) : 
This medication is an enzyme, prescribed for heart attack, pulmonary embolism and deep vein thrombosis. It breaks up and dissolves blood clots that can block arteries.  
When it is not to be taken (Contraindications): 
Contraindicated in patients with high blood pressure, recent stroke, brain tumor, peptic ulcer, intestinal ulcer, inflammation of pancreas, blood clot defects due to liver or kidney disease, recent surgery, childbirth, trauma, active internal bleeding, during pregnancy and hypersensitivity.

Pregnancy Category :

A B C D X
Category C : Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

Dosage & When it is to be taken : 
IV- Acute MI- 1.5 million units as a single dose immediately after onset of symptoms.
Pulmonary thromboembolism; Arteriovenous occlusions Loading dose: 250,000 units via infusion. Maintenance: 100,000 u/hour for 24-72 hour depending on the condition treated.
How it should be taken : 
It comes as a solution for injection to be administered by a healthcare provider into the vein.
Warnings and Precautions : 
* Caution should be exercised in patients with history of vision problems due to diabetes, bleeding disorders, high blood pressure, infection in heart valves, recent biopsy or surgery, recent injury, any allergy and elderly.
Side Effects : 
Most Common- Bleeding.
Allergic Reactions- Fever, shivering, difficulty in breathing, asthma, rash, hives, itching, flushing, nausea and headache.
Respiratory- Respiratory depression.
Other Precautions : 
*Avoid excess dosage.
Storage Conditions : 
Store unopened vials at controlled room temperature (15-30°C) and in an airtight container.

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Member Comments ( 1 )
my wife was choosen to inject this medicine while she had acute cheast pain thinking that she had a massive arterial attack. she is diabatic for last 25 years having good control of blood sugar by onglyza 5 mg tab associated with met form ajulux 2 mf. she is ok now but really she did suffer with heart attack as DR.THOUGHT. SO I AM ENQUIRING ABOUT SIDE EFFECT.NO BLEEDING ETC.
(Posted by MAITY45, India Date : 9/29/2012 )

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Reference  

  • Food and Drug Administration (FDA)
  • National Institutes of Health (NIH)
  • PubMed
  • CIMS
  • Indian Pharma Reference Guide 2012
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