Generic Name : Streptokinase Pronunciation : strep-toe-KYE-nase Therapeutic Classification : Enzymes ICD Code : Y43.6
India- Cardiostrep Inj, Eskinase Vial, Fibrokinase Vial, Haemokinase Inj, Icikinase Vial, Kabikinase Inj, Myokinase Vial, Niskinase Inj, Prokinase Vial, Shankinase Vial, Stpase Inj Vial, Streplife Vial, Streptase Vial, Streptoken Vial, Streptokinase Vial, Streptonase Vial, Stukinase Inj, Thrombosolv Vial, Zykinase Vial.
International- Streptase. Overview : Note: This brand is not available in US market. Why it is prescribed (Indications) :
This medication is an enzyme, prescribed for heart attack, pulmonary embolism and deep vein thrombosis. It breaks up and dissolves blood clots that can block arteries. When it is not to be taken (Contraindications):
Contraindicated in patients with high blood pressure, recent stroke, brain tumor, peptic ulcer, intestinal ulcer, inflammation of pancreas, blood clot defects due to liver or kidney disease, recent surgery, childbirth, trauma, active internal bleeding, during pregnancy and hypersensitivity.
Dosage & When it is to be taken :
IV- Acute MI- 1.5 million units as a single dose immediately after onset of symptoms.
Pulmonary thromboembolism; Arteriovenous occlusions Loading dose: 250,000 units via infusion. Maintenance: 100,000 u/hour for 24-72 hour depending on the condition treated. How it should be taken :
It comes as a solution for injection to be administered by a healthcare provider into the vein. Warnings and Precautions :
* Caution should be exercised in patients with history of vision problems due to diabetes, bleeding disorders, high blood pressure, infection in heart valves, recent biopsy or surgery, recent injury, any allergy and elderly.
Side Effects :
Most Common- Bleeding.
Allergic Reactions- Fever, shivering, difficulty in breathing, asthma, rash, hives, itching, flushing, nausea and headache.
Respiratory- Respiratory depression.
*Avoid excess dosage. Storage Conditions :
Store unopened vials at controlled room temperature (15-30°C) and in an airtight container.
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