Medindia » Medication Manual » Stavudine

Stavudine

Latest prescription information about Stavudine. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
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Generic Name : Stavudine
Pronunciation : STAV-yoo-deen
Therapeutic Classification : Antiretroviral Agents
ICD Code : Y41.5
Trade Name(s): 
India- Emduo Susp, Emduo-30, Emduo-40, Emduo-E-30, Emduo-E 40, Emduo-Jr, Emduo-N, Emtri 30, Emtri 40, Emtri Susp, Emtri Jr, Stadine, Stavex, Stavex 40, Stavir, Stv, Stv Comp, Stv Comp-3, Stv Plus, Trimune-4, Virostav.
International- Zerit.
Why it is prescribed (Indications) : 
This medication is a nucleoside analog reverse transcriptase inhibitor (NARTI), prescribed for HIV/AIDS. It blocks the growth of HIV.
When it is not to be taken (Contraindications): Hypersensitivity.

Pregnancy Category :

A B C D X
Category C : Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

Dosage & When it is to be taken : 
Adult: PO – The recommended dose is 30 mg for people who have less than 60kg body weight. Greater than 60 kg/BW: 40 mg two times per day.
How it should be taken : 
It comes as a capsule and liquid to take by mouth with or without food.
Warnings and Precautions : 
* Caution should be exercised in patients with history of liver or kidney disease, sugar, elderly, during pregnancy and breastfeeding.
* Monitor patients for development of peripheral neuropathy.
* Redistribution/accumulation of body fat including central obesity may occur.
Side Effects : 
Nausea, vomiting, diarrhea, rash, liver damage and inflammation of pancreas.
Other Precautions : 
*Avoid excess dosage.
Storage Conditions : 
Keep out of the reach of children. Store away from heat and direct light.
Store the oral solution in refrigerator. However, keep the medicine from freezing.

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Reference  

  • Food and Drug Administration (FDA)
  • National Institutes of Health (NIH)
  • PubMed
  • CIMS
  • Indian Pharma Reference Guide 2012
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