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Spironolactone

Latest prescription information about Spironolactone. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
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Generic Name : Spironolactone
Pronunciation : speer on oh lak' tone
Therapeutic Classification : diuretics
Trade Name(s): 
India- Aldactide Tab, Aldactone Tab, Spilactone Tab, Spilactone-T Tab.
International- Aldactone.
Why it is prescribed (Indications) : 
This medication is a potassium-sparing diuretic, prescribed for hyperaldosteronism, low potassium levels, and for edema (fluid retention) caused by various conditions.

When it is not to be taken (Contraindications): 


Contraindicated in patients with anuria (absence of urination), and significant impairment of kidney function.

Pregnancy Category :

A B C D X
Category C : Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.


When it is to be taken : 
Adult- PO- The recommended dose range is 50 to 400mg/day for 3 to 4 weeks.
How it should be taken : 
It comes as a tablet to take by mouth, with food.
Special Instruction : 
* Caution should be exercised in patients with history of changes in blood minerals, kidney, liver, or heart disease, diabetes or high level of urea or nitrogen in blood, any allergy, who are taking other medications, elderly, children, during pregnancy and breastfeeding.
* It may cause dizziness or drowsiness, do not drive a car or operate machinery while taking this medication.
Side Effects : 
Gastrointestinal - Gastric bleeding, ulceration, stomach inflammation, diarrhea, cramping, nausea and vomiting.
Genitourinary - Breast enlargement in male, absence of menstrual period, painful erection, irregular periods, breast cancer, kidney impairment and postmenopausal bleeding.
Blood - Decrease in blood counts.
Hypersensitivity - Fever, hives, shock, inflammation of veins and skin lesions.
Metabolic - Elevated blood potassium level.
Central Nervous system - Mental confusion, incoordination, headache, drowsiness and lethargy.
Liver - Liver damage.
Other Precautions : 
* Avoid excess dosage.
Storage Conditions : 
Store it at room temperature (25°C).

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