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Sparfloxacin

Latest prescription information about Sparfloxacin. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
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Generic Name : Sparfloxacin
Pronunciation : spar FLOX a sin
Therapeutic Classification : Antibiotics
ICD Code : Y40.8
Trade Name(s): 
India- Actiflox, Acuspar, Alps, Artispar, Aspar, Atospar, Bal-Spar, Bluspar, Canspar, Cinospar, Dinor, Efospar, E-Spar, Excelspar, Flotome, Floxpar, Forspac, Guspar , Inspar-200, Jugam, Kespar, Klaspar, Modspar, Novospar, Onespar, Ospar, Paar, Parcy, Prespar, Prozlox, Pufam, Quspar, Rexpar, Scat, Seflo, Selax , Sfc, Sipar, Span, Sparact, Sparbact, Sparbic, Sparcin, Sparcip, Sparcure, Spardac, Spardic, Spare, Sparflin, Sparflo, Sparind, Sparinta, Spariz, Sparkare, Sparkem, Sparkind, Sparkle, Sparlet Tab, Sparlex, Sparlox, Sparmax, Sparnat, Sparnij, Sparo, Sparovir, Sparquin, Sparsun, Spart, Sparta, Spartab, Spartec, Spartin, Sparvista, Sparwar, Sparx, Sparz, Sparzid, Spaxin, Spicy, Spiral, Spoxin, Suplo-S, Swespar, Tekspar, Torospar, Unospar, Vanspar, Varspar, Wyspar, Zespar, Zospar, Zotaspar, Zufox.
International- Zagam.
Overview : 
Note: It has been withdrawn from the U.S. market.
Why it is prescribed (Indications) : 
This medication is a fluoroquinolone antibiotic, prescribed for community-acquired pneumonia, and chronic bronchitis. It fights bacteria in the body.
When it is not to be taken (Contraindications): Contraindicated in patients who are taking antiarrhythmic drugs, and hypersensitivity.

Pregnancy Category :

A B C D X
Category C : Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

Dosage & When it is to be taken : 
Adult: PO- The recommended dose is 100-300 mg/day in 1-2 divided doses.
How it should be taken : 
It comes as a tablet to take by mouth, with or without food.
Warnings and Precautions : 
* Caution should be exercised in patients with history of kidney, liver, or heart disease, epilepsy, G6PD deficiency, myasthenia gravis, slow heart rate, electrolyte disturbances, who are taking other medications, during pregnancy and breastfeeding.
* Avoid exposure to strong sunlight.
* Drink adequate fluid to reduce risk of crystalluria (presence of crystals in urine).
Side Effects : 
Most Common - Photosensitivity reaction, diarrhea, nausea, headache, indigestion, dizziness, sleeplessness, abdominal pain, itching, taste perversion, QT interval prolongation, vomiting, flatulence, and dilatation of blood vessels.
Body As A Whole - Fever, chest pain, generalized pain, allergic reaction, cellulitis, back pain, chills, face swelling, uneasiness, injury, shock, infection, mucous membrane disorder, neck pain, rheumatoid arthritis.
Heart - Palpitations, electrocardiogram abnormal, high blood pressure, fast or slow heart rate, chest pain, abnormal heart rhythm, atrial flutter, bleeding, migraine, and low blood pressure.
Gastrointestinal - Constipation, loss of appetite, gum inflammation, oral infection, mouth ulcer, tongue disorder, tooth disorder, stomach flu, increased appetite, mouth ulceration, flatulence and vomiting.
Blood - Bluish, bruising, disease of the lymph nodes.
Metabolic - Gout, swelling in the extremities, thirst.
Musculoskeletal - Joint pain, joint inflammation, and muscle pain.
Central Nervous System - Tingling, nervousness, drowsiness, abnormal dreams, dry mouth, depression, tremor, anxiety, confusion, hallucinations, sleep disorder, fainting, abnormal gait, agitation, lightheadedness, emotional lability, abnormal thinking, memory loss, and twitching.
Respiratory - Asthma, nosebleed, pneumonia, runny nose, inflammation of pharynx, bronchus, coughing up blood, sinusitis, cough increased, difficulty in breathing, lung disorder, pleural disorder.
Skin - Rash, dry skin, herpes simplex, sweating, hives, skin inflammation, pimples, hair loss, skin discoloration, and herpes zoster.
Eye and ENT - Ear pain, lazy eye, sensitivity to light, ringing in the ear, eye inflammation, double vision, abnormality of accommodation, inflammation of eyelid, ear disorder, eye pain, tear disorder, and ear infection.
Genitourinary - Vaginal inflammation, painful urination, breast pain, painful menstrual period, blood in urine, irregular periods, night time urination, urinary tract infection, kidney pain, white discharge, and vulvovaginal disorder.
Other Precautions : 
* Avoid excess dosage.
Storage Conditions : 
Store it at controlled room temperature (20 to 25°C).

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Reference  

  • Food and Drug Administration (FDA)
  • National Institutes of Health (NIH)
  • PubMed
  • CIMS
  • Indian Pharma Reference Guide 2012
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