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Sitagliptin - Indications, Dosage, Side Effects and Precautions

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Information about Sitagliptin

Generic Name : Sitagliptin
Up-to-date prescription details regarding Sitagliptin are provided here.

Pronunciation : sit a glip' tin

Learn the correct pronunciation of the Sitagliptin, understand it's uses, recommended dosages, its indications, how to take, when to take, when not to take, side effects, special precautions, warnings and its and its storage instructions.
You will also find a list of the medication's International and Indian brand or trade names, as well as its pricing information. For verification of the information presented on this page or for additional clarifications, it's advisable to consult your doctor.


ICD Code : Y52.6 Therapeutic Classification : Antihyperglycemics

Trade Names/Brand Names of Sitagliptin

India :

International :


Januvia Tab, Zita, Istavel

Why is Sitagliptin Prescribed? (Indications)

Sitagliptin is indicated to improve glucose control in adults with type 2 diabetes mellitus along with diet and exercise.

When should Sitagliptin not be taken? (Contraindications)

• There is a previous history of a severe allergy to Sitagliptin
• Patients with type 1 diabetes
• Diabetic ketoacidosis
• Previous history of pancreas inflammation

What is the dosage of Sitagliptin?

Sitagliptin is available as an oral tablet.
Strengths: 50mg, 100mg

How should Sitagliptin be taken?

It should be taken by mouth once daily with or without food.
The dose is 25-50mg in patients with kidney problems

What are the warnings and precautions for Sitagliptin?

•1. Avoid alcohol consumption while taking Sitagliptin

• 2. Sitagliptin may lead to low blood sugar, monitor blood sugar regularly.

What are the side effects of Sitagliptin?

Metabolic- Low blood sugar with other medications.
Central Nervous System- Headache.
Eye and ENT- Inflammation of nasopharynx.
Gastrointestinal- Diarrhea, nausea, inflammation of pancreas.
Respiratory- Upper respiratory tract infection.
Musculoskeletal-Joint pain, muscle pain, pain in extremity and back pain.

What are the other precautions for Sitagliptin?

Caution is needed in patients with:
• Patients under 18 years of age
• Kidney problems
• Liver problems
• Pancreas problems
• Pregnant and lactating women

What are the Drug Interactions of Sitagliptin?

Do not take Sitagliptin with:
• Digoxin
• Sulphonylureas
• Insulin

What are the storage conditions for Sitagliptin?

Store it at room temperature and in an airtight container. Keep away from children.
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