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Generic Name : Simvastatin
Pronunciation : SIM-va-STAT-in
Therapeutic Classification : antilipemics
Trade Name(s):
India- Biosim Tab, Sim Tab, Simcard Tab, Simchol Tab, Simlip Film-Coated Tab, Simlo Tab, Simstat Tab, Simstat-N Tab, Simvas Tab, Simvastol Tab, Simvastol-N Tab, Simvax Tab, Simvin Tab, Simvo Tab, Simvofix Tab, Simvotin Fc-Tab, Simvotin Tab, Sin Tab, Starstat Tab, Svt Tab, Vastatin Tab, Zosta Tab. International- Zocor. This medication is an HMG-CoA reductase inhibitor, also known as a "statin", used for lowering high cholesterol and triglycerides in certain patients with appropriate diet. It reduces the risk of cardio vascular diseases, and blood vessels blockage. When it is not to be taken (Contraindications):
When it is to be taken : The recommended dose is 5-20mg/day by orally. The maximum dose is 40mg/day. How it should be taken : It comes as a tablet to take by mouth (orally). It is usually taken one to three times a day, with or without food. Avoid excessive consumption (> 1 L/day) of grapefruit juice. Special Instruction : * Caution should be exercised patients with history of liver disease. * It may lead to rapid breakdown of skeletal muscle (rhabdomyolysis), severe infection, low blood pressure, major surgical trauma, uncontrolled seizures or severe metabolic, endocrine and electrolyte disorder. * Avoid drinking alcohol otherwise it may result in liver failure. * This medication should be used with extreme caution in children younger than 10 years old and in those who have not reached puberty. Discontinue treatment if there is marked or persistent increase in serum-aminotransferase concentrations. Side Effects : Central Nervous System- Headache, dizziness, sleeplessness, depression. Gastrointestinal- Nausea, flatulence, distortion of the sense of taste, abdominal pain, diarrhea, constipation. Eye- Lens opacities, blurring of vision. Metabolic- Serum transaminases and CPK elevations. Musculoskeletal- Muscle pain and muscle weakness. Miscellaneous- Heartburn, hypersensitivity, sexual dysfunction, and upper respiratory symptoms. *Avoid changing the dose with out doctor's advice. Storage Conditions : Oral: Store at 5-30°C. Store it in an airtight container and keep away from children. |
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