Silymarin - Drug Information

Generic Name : Silymarin | Pronunciation : SILL-ee-MAR-inn

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Latest prescription information about Silymarin. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
Therapeutic Classification : Antioxidants
Trade Name(s): 
India :  More...

International : Hepasil, Heptosil, Liprotec, Sarim, Silimarin, Silirin

Why it is prescribed (Indications) : 
This medication is a herb, prescribed for liver disease.  

When it is not to be taken (Contraindications): 

Pregnancy Category :


Category N : Not yet classified.

Dosage & When it is to be taken : 
Adult: PO- The recommended dose is 140 mg 2-3 times/day.

How it should be taken : 
It comes as a tablet, capsule, and syrup to take by mouth, with food.

Warnings and Precautions :  Caution needed in patients with history of hepatic encephalopathy (confusion, altered level of consciousness and coma as a result of liver failure), and in pregnant and breastfeeding women.

Side Effects : Abdominal bloating, diarrhea, flatulence, loss of appetite, nausea and stomach upset.

Other Precautions :  Avoid excess dosage.

Storage Conditions : Store it at room temperature.

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how dose this medicine effective against hepatities c?
tenthcaller  Tuesday, April 09, 2013
SILYMARIN, a mix of bioflavonoids, has properties that protect the liver. It acts on the liver
1. by changing the structure of the outer liver cell
membrane, thereby preventing liver toxins and poisons from entering the interior cell.
2. by stimulating protein synthesis in liver cells which
generates DNA and RNA, thereby helping to regenerate liver cells without stimulating growth of malignant cells.
3. by inhibiting the enzyme lipoxygenase, which forms leukotrienes from oxidized polyunsaturated fats that damage the liver.
4. by acting as an antioxidant (silymarin is at least ten times more powerful than vitamin E).
5. by increasing the gluthathione (GSE) content of the liver.

KUKREJA  Thursday, October 22, 2009

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