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Sevoflurane

Latest prescription information about Sevoflurane. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
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Generic Name : Sevoflurane
Pronunciation : see-voe-FLOO-rane
Trade Name(s): 
International- Sevorane Inhalation and Soln, Ultane.
Why it is prescribed (Indications) : 
This medication is a halogenated hydrocarbon, acts as a general anesthetic during surgery either alone or combined with others. It is given by inhalation. This helps produce more effective anesthesia in some patients.

When it is not to be taken (Contraindications): 


Contraindicated in patients with known or suspected susceptibility to malignant elevated body temperature, previous hypersensitivity.

Pregnancy Category :

A B C D X
Category B : Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.


When it is to be taken : 
Inhalation Via a calibrated vaporiser: Induction: Up to 5% v/v w/ oxygen or a mixture of oxygen and nitrous oxide. Maintenance: 0.5-3% v/v w/ or w/o nitrous oxide.
How it should be taken : 
It comes as a inhaler, to inhale by mouth.
Special Instruction : 
*Maintenance of blood movement stability is important in patients with coronary artery disease.
* It may make the patient drowsy, tired, or weak for a while after they receive it. Do not drive a car, or operate moving machinery, while taking this medication.
*Caution needed for patients with history of raised intracranial pressure; heart, lung, kidney, or liver impairment, elderly, and obese patients.
Side Effects : 
Central Nervous System- Agitation, seizure-like activity. movement disorder in children.
Heart- Low blood pressure, malignant elevated body temperature,
Respiratory- Difficult in breathing, increased cough.
Gastrointestinal- Salivation, nausea, vomiting.
Genitourinary- Acute kidney failure, shivering, postoperative liver inflammation.
Other Precautions : 
*Avoid alcoholic beverages.
Storage Conditions : 
Store at 15-30°C. Store it in airtight container.

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