Medindia » Consumer Health » Medication Manual » Sertraline

Sertraline

Latest prescription information about Sertraline. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
Email Email Save this page Save Syndicate Syndicate
Generic Name : Sertraline
Pronunciation : ser' tra leen
Therapeutic Classification : psychotherapeutics
Trade Name(s): 
India- Actiser Tab, Aderta Tab, Censir Tab, Daxid Film-Coated Tab, Dazolin Tab, Depsert Tab, Episod Tab, Inosert Fc-Tab, Lindep Tab, Line Tab , L-Peez S Tab, Medisert Tab, Mentolift Tab, Mentolift-Plus Tab, Obzin Tab, Relax-S Tab, Resert Tab, Restalin Tab, Retalin Tab, Serdep Film-Coated Tab, Serenata Tab, Serjet Tab, Serlift Tab, Serlin Tab, Serne Tab, Serta Tab, Sertacare Tab, Sertacin Tab, Sertawin Tab, Sertil Tab, Sertima Tab, Sertrax Tab, Setalin Film-Coated Tab, Setex Tab, Setex-A Tab, Syms Tab, Tralin Tab, Tras Tab, User Tab, Xsert Tab, Zert-Od Tab, Zosert Tab, Zotral Film-Coated Tab.
International- Zoloft .
Why it is prescribed (Indications) : 
This medication is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class, prescribed for major depression, obsessive-compulsive disorder panic attacks, and social anxiety disorder. It increases the amounts of serotonin, a natural substance in the brain that helps maintain mental balance.

When it is not to be taken (Contraindications): 


Contraindicated in patients are taking or have taken linezolid, methylene blue, a monoamine oxidase inhibitor (MAOI), selegiline, or St. John's wort within the last 14 days, and hypersensitivity.

Pregnancy Category :

A B C D X
Category C : Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.


When it is to be taken : 
PO- The dose in depression and obsessive- compulsive syndrome is 50mg/day, which can be increased as per requirement to up to 200 mg/day. The recommended dose in children is 25 mg/day.
How it should be taken : 
This medication available in the form of tablet and a concentrate liquid to be taken by mouth, with or without food.
Special Instruction : 
*Caution should be exercised in patients with history of hypomania and seizure disorders, liver or kidney damage, heart disease, recent heart attack, bleeding disorders, diabetes and angle-closure glaucoma.
*Discontinue treatment if seizures develop or if there is an increase in seizure frequency.
*Monitor for signs of clinical worsening, suicidality and unusual changes in behavior especially during the initial treatment period or when there are dosage adjustments.
Side Effects : 
Heart- Palpitations, chest pain; increased coagulation times, slow heart beat, AV block, abnormal heart rhythms, QT-interval prolongation, fast heart beat.
Central Nervous System-Headache, sleep disorder, drowsiness, dizziness, fatigue, general discomfort, tremor, increased libido, agitation, nervousness, anxiety, aggressive reaction, hyperactivity, tingling, weakness.
Skin- Sweating, rash, photosensitivity, inflammatory destruction of blood vessels.
Eye and ENT-Abnormal vision, tinnitus, blindness, cataract, inflammation of the optic nerve.
Gastrointestinal-Nausea, diarrhea, dry mouth, upset stomach, abdominal pain, loss of appetite, constipation, vomiting, increased appetite, inflammation of pancreas.
Genitourinary- Abnormal ejaculation, sexual dysfunction, urinary incontinence, impotence, potentially harmful, acute renal failure.
Blood- Purple or discolorations on the skin, lowered white blood cell count, blood disorder, lupus-like syndrome, reduction in the number of red cells, serum sickness, decrease in platelets.
Liver- Elevated liver enzymes, increased bilirubin, liver enlargement, jaundice, liver failure.
Metabolic- Increased weight, high blood sugar, low thyroid level.
Respiratory- Nose bleed, inflammation of sinus, runny nose. Miscellaneous- Pain, fever, pain, weight loss; back pain, muscle pain, yawning, anaphylaxis.
Other Precautions : 
*Withdrawal should be gradual.*Consult your doctor during pregnancy and breastfeeding.
Storage Conditions : 
Oral: Store at 15-30°C.

Comment & Contribute
Comments should be on the topic and should not be abusive. Comments are normally moderated and are reviewed after they are posted.
* Your comment can be maximum of 2500 characters
I agree to the terms and conditions
If you have a question about health related issues, you can now post it in our Ask An Expert section on our community website Medwonders.com and get answers from our panel of experts.

Browse the Drugs alphabetically

Drugs Index
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z