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Secobarbital

Latest prescription information about Secobarbital. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
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Generic Name : Secobarbital
Pronunciation : see koe bar' bi tal
Therapeutic Classification : Sedative-hypnotic Drugs
ICD Code : Y47.0
Trade Name(s): 
International- Seconal.
Why it is prescribed (Indications) : 
This medication is a barbiturate, prescribed for insomnia (difficulty falling asleep or staying asleep). It is also used to relieve anxiety before surgery.  It works by slowing activity in the brain.
When it is not to be taken (Contraindications): Contraindicated in patients with porphyria, liver impairment, respiratory and hypersensitivity.

Pregnancy Category :

A B C D X
Category D : There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

Dosage & When it is to be taken : 
Adults - The recommended dose is:
As a hypnotic- 100 mg at bedtime.
Preoperatively- 200 to 300 mg 1 to 2 hours before surgery.
Pediatric Patients - Preoperatively- 2 to 6 mg/kg, with a maximum dosage of 100 mg.
How it should be taken : 
It comes as a capsule to take by mouth, with or without food.
Warnings and Precautions : 
* Caution should be exercised in patients with history of alcohol abuse or dependence, depression, suicidal thoughts, any allergy, who are taking other medications, during pregnancy and breastfeeding.
* It may cause drowsiness, do not drive a car or operate machinery while taking this medication.
* Avoid alcohol consumption.
Side Effects : 
Central Nervous System - Drowsiness, agitation, confusion, restlessness, incorodination, CNS depression, nightmares, nervousness, psychiatric disturbance, hallucinations, sleeplessness, anxiety, dizziness and abnormality in thinking.
Respiratory - Difficulty in breathing.
Heart - Slow heart rate, low blood pressure and fainting.
Gastrointestinal - Nausea, vomiting and constipation.
Miscellaneous - Headache, injection site reactions, hypersensitivity reactions (shock, skin rashes, skin inflammation), fever and liver damage.
Other Precautions : 
* Avoid excess dosage.
Storage Conditions : 
Store it at room temperature.

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Reference  

  • Food and Drug Administration (FDA)
  • National Institutes of Health (NIH)
  • PubMed
  • CIMS
  • Indian Pharma Reference Guide 2012
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