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Saquinavir

Latest prescription information about Saquinavir. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
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Generic Name : Saquinavir
Pronunciation : sa-KWIN-a-veer
Trade Name(s): 
International- Invirase , Fortovase.
India- Saquin Tab.
Why it is prescribed (Indications) : 
This medication is a protease inhibitor, prescribed for human immunodeficiency virus (HIV) infection in patients with or without acquired immunodeficiency syndrome (AIDS) with other medication. It slows the spread of HIV in the body.

When it is not to be taken (Contraindications): 


Contraindicated in patients with severe liver damage, in breastfeeding women, and hypersensitivity.

Pregnancy Category :

A B C D X
Category B : Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.


When it is to be taken : 
PO- HIV infection Combined with other antiretroviral: In patients more than 16 years: 1 g twice daily with ritonavir. Take antiretroviral medications (ARVs) as soon as possible after exposure to HIV 1g twice daily with ritonavir and other antiretroviral and continue for 4 weeks if tolerated.
How it should be taken : 
It comes as a tablet and capsule. It is taken twice a day on a full stomach but can be delayed up to 2 hours after a meal. A soft gelatin capsule is also available that has to be taken 3 times a day.
Special Instruction : 
*Caution needed for pregnant women, adolescents <16 years, elderly, patients with history of liver or kidney damage, diabetes, group of genetic disorders.
*It may increase triglyceride and lipid levels.
*It may affect your blood sugar. Check blood sugar regularly.
Side Effects : 
Gastrointestinal- Nausea, vomiting, diarrhea, taste disturbance, abdominal pain, loss of appetite, increased appetite, excessive stomach gas.
Central Nervous System-Fatigue, sleep disturbances, headache, dizziness.
Skin- Itching, and exacerbation of diabetes, in growing toenails and nail infection of the great toes, hypersensitivity.
Blood- Blood disorders, Irregular, prolonged heavy menstruation. Miscellaneous- Sexual dysfunction.
Other Precautions : 
*It may cause dizziness or vision problem. Do not drive a car, operate machinery, or do anything else that could be dangerous.
Storage Conditions : 
Store at 25°C. Keep in an airtight container. Keep away from children.

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