Generic Name : Samarium SM 153 Lexdronam Pronunciation : sa-MAR-ee-um Sm 153 lex-ID-roe-nam Therapeutic Classification : Radiopharmaceutical, Antineoplastic
International- Quadramet. Why it is prescribed (Indications) :
This medication is a radioisotope, prescribed for relieving the bone pain that may occur with confirmed osteoblastic metastatic bone lesions. When it is not to be taken (Contraindications):
Dosage & When it is to be taken :
IV- The recommended dose is 1.0 mCi/kg, administered intravenously over a period of one minute. How it should be taken :
It comes as a solution for injection to be administered by a healthcare provider into the vein. Warnings and Precautions :
* Caution should be exercised in patients with history of heart failure, irregular heartbeat, kidney impairment, urinary incontinence, bone marrow depression, blood disorders, poor immunity, low blood calcium levels, any allergy, who are taking other medications, during pregnancy and breastfeeding.
* Avoid live immunizations/vaccinations during the treatment period.
* Avoid contact with people who have infections.
* It may reduce platelet counts; avoid injury or bruising. Side Effects :
Body as a Whole - Worsening of the condition, fever, chills and infection.
Heart - Abnormal heart rhythm, chest pain and high or low blood pressure.
Gastrointestinal - Abdominal pain, diarrhea, nausea and vomiting.
Blood - Clotting disorder, anemia, decrease in white blood cells, and platelets, lymph node disease, blood in urine and nosebleed.
Musculoskeletal - Muscle pain, weakness and fracture.
Central Nervous System - Dizziness, tingling, spinal cord compression and stroke.
Respiratory - Lung inflammation and increased cough.
Skin - Bruising and rash.
* Avoid excess dosage. Storage Conditions :
Normally handled and stored by healthcare providers.
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