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Generic Name : Ruxolitinib
Trade Name(s): International- Jakafi. Why it is prescribed (Indications) : This medication is a kinase inhibitor, prescribed for high-risk myelofibrosis. It blocks certain substances (JAK1 and JAK2) that are involved in myelofibrosis. When it is not to be taken (Contraindications): Contraindicated in patients with known hypersensitivity.
Dosage & When it is to be taken : PO- The starting dose is 20 mg 2 times per day, for patients with platelet count greater than 200 X 109/L. How it should be taken : It comes as a tablet to take by mouth, with or without food. Warnings and Precautions : * Caution should be exercised in patients with history of liver or kidney impairment, patients on dialysis, during pregnancy and breastfeeding. * It may cause dizziness, avoid performing any hazardous activity while taking this medication. * Patient may develop with certain types of infection; discuss with your healthcare provider before taking this medication. * It may reduce platelet counts; avoid injury or bruising. * Monitor complete blood count regularly while taking this medication. Side Effects : Most Frequent - Thrombocytopenia and anemia. Miscellaneous - Bruising, dizziness, headache, urinary tract infection, weight gain, flatulence, herpes zoster. * Avoid excess dosage. Storage Conditions : Store it at room temperature (20° to 25°C). |
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