Medindia » Medication Manual » Ruxolitinib

Ruxolitinib

Latest prescription information about Ruxolitinib. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
Email Email print Print Save this page Save Syndicate Syndicate
Generic Name : Ruxolitinib
Trade Name(s): 
International- Jakafi.
Why it is prescribed (Indications) : 
This medication is a kinase inhibitor, prescribed for high-risk myelofibrosis. It blocks certain substances (JAK1 and JAK2) that are involved in myelofibrosis.
When it is not to be taken (Contraindications): Contraindicated in patients with known hypersensitivity.

Pregnancy Category :

A B C D X
Category C : Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

Dosage & When it is to be taken : 
PO- The starting dose is 20 mg 2 times per day, for patients with platelet count greater than 200 X 109/L.
How it should be taken : 
It comes as a tablet to take by mouth, with or without food.
Warnings and Precautions : 
* Caution should be exercised in patients with history of liver or kidney impairment, patients on dialysis, during pregnancy and breastfeeding.
* It may cause dizziness, avoid performing any hazardous activity while taking this medication.
* Patient may develop with certain types of infection; discuss with your healthcare provider before taking this medication.
* It may reduce platelet counts; avoid injury or bruising.
* Monitor complete blood count regularly while taking this medication.
Side Effects : 
Most Frequent - Thrombocytopenia and anemia.
Miscellaneous - Bruising, dizziness, headache, urinary tract infection, weight gain, flatulence, herpes zoster.
Other Precautions : 
* Avoid excess dosage.
Storage Conditions : 
Store it at room temperature (20° to 25°C).

Comment & Contribute
Comments should be on the topic and should not be abusive. Comments are normally moderated and are reviewed after they are posted.
* Your comment can be maximum of 2500 characters
I agree to the terms and conditions
If you have a question about health related issues, you can now post it in our Ask An Expert section on our community website Medwonders.com and get answers from our panel of experts.
Member Comments ( 6 )
plz give me details of cost n from where i get this tablet in india thanks
mail2shailendra@gmail.com

(Posted by shailu86, India Date : 1/4/2013 )
Please Inform me the Sales manager or Marketing manager's( Ruxolitinib tablets )Phone No or email address by my email : laxmi1680@rediffmail.com
(Posted by nirmalDasgupta, India Date : 9/5/2012 )
i was diagnosed with myelofibrosis,i required Ruxolitinib tablets . please contact: uttikrishnamurthy@gmail.com
(Posted by uttikrishnamurthy, India Date : 6/30/2012 )
Pl. suggest from where can I get the Tablets Ruxolitinib for Myelofibrosis & what is cost of each Tablet.
(Posted by vijay49, India Date : 4/29/2012 )
i was diagnosed with myelofibrosis from last 2 year, i required Ruxolitinib tablets . please contact engg.rahul.rd@gmail.com,
+91-9718535628

(Posted by rahul_dev, India Date : 4/8/2012 )
View All Comments (6)

Browse the Drugs alphabetically

Reference  

  • Food and Drug Administration (FDA)
  • National Institutes of Health (NIH)
  • PubMed
  • CIMS
  • Indian Pharma Reference Guide 2012
Drugs Index
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z