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Rotavirus Vaccine

Updated on : September - 2012
Latest prescription information about Rotavirus Vaccine. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
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Generic Name : Rotavirus Vaccine
Pronunciation : ROE-ta-vye-rus VAX-een, lyve
Therapeutic Classification : Immunizing Agents
ICD Code : Y59.0
Trade Name(s): 
International- Rotarix, RotaTeq.
Why it is prescribed (Indications) : 
This medication is a vaccine, prescribed for the prevention of rotavirus gastroenteritis caused by G1 and non-G1 types in infants and children. It helps the immune system to protect against rotavirus.
When it is not to be taken (Contraindications): Contraindicated in patients with uncorrected congenital malformation of the gastrointestinal tract.

Pregnancy Category :

A B C D X
Category C : Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

Dosage & When it is to be taken : 
The vaccination series consists of two 1-mL doses administered orally. The first dose should be administered to infants beginning at 6 weeks of age. There should be an interval of at least 4 weeks between the first and second dose. The 2-dose series should be completed by 24 weeks of age.
How it should be taken : 
It comes as a solution to take by mouth.
Warnings and Precautions : 
* Caution should be exercised in patients with history of gastrointestinal disorders, poor immunity and any allergy.
* The healthcare provider should inform the parents or guardians about the possible adverse reactions.
Side Effects : 
Most Common- Fussiness, irritability, cough, runny nose, fever, vomiting and diarrhea.
Serious- Death and intestinal blockage.
Blood and Lymphatic- Decrease in platelets and bruising.
Gastrointestinal- Blood in the stools and intussusception.
General- Maladministration.
Other Precautions : 
*Avoid excess dosage.
Storage Conditions : 
Vial- Store it in refrigerator (2° to 8°C).
Diluent- The diluent may be stored at a controlled room temperature 20° to 25°C. Do not freeze. Discard if the diluent has been frozen.
♦ Safety Labeling Changes Approved By FDA

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Reference  

  • Food and Drug Administration (FDA)
  • National Institutes of Health (NIH)
  • PubMed
  • CIMS
  • Indian Pharma Reference Guide 2012
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