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Rosuvastatin

Updated on : October - 2012
Latest prescription information about Rosuvastatin. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
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Generic Name : Rosuvastatin
Pronunciation : roe soo' va sta tin
Therapeutic Classification : Antilipemics
ICD Code : Y52.6
Trade Name(s): 
India- Bestor Tab, Fortius Tab, Fortius-20 Tab, Ldnil Film-Coated Tab, Novastat Tab, Razel Tab, Rostar Tab, Rosuvas Tab, Rosuvastat Tab, Rosyn Tab, Rovalip Tab, Rozavel Tab, Rozucor Tab, Turbovas Tab, Zyrova Tab.
International- Crestor.
Why it is prescribed (Indications) : 
This medication is used to reduce the cholesterol in patients with obesity problem. It is a HMG-CoA reductase inhibitor (statin). It slows the production of cholesterol in the body. 
When it is not to be taken (Contraindications): 
Contraindicated in patients with liver disease, during pregnancy and breastfeeding; hypersensitivity.

Pregnancy Category :

A B C D X
Category X : Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use of the drug in pregnant women clearly outweigh potential benefits.

Dosage & When it is to be taken : 
PO- Initial: The recommended dose is 5 to10 mg/day may increase slowly to 20 mg/day if needed. Max: 40 mg/day.
How it should be taken : 
It comes as a tablet to take by mouth. It is usually taken once a day with or without food.
Warnings and Precautions : 
* Not to be used in patient with acute, serious condition suggestive of muscular diseases(myopathy) or predisposing to the development of kidney failure secondary to rapid breakdown of skeletal muscle(rhabdomyolysis) e.g. sepsis, hypotension, major surgery, trauma, severe metabolic, endocrine and electrolyte disorders or uncontrolled seizures.
* Caution should be exercised in patients with history of liver disease and alcoholism.
* Discontinue treatment if there is marked or persistent increase in serum aminotransferase concentrations, significant increase in creatinine phosphokinase or evidence of muscular diseases.
*Monitor liver function regularly while taking this medication.
Side Effects : 
Central Nervous System- Headache, dizziness, tingling, lack of energy, sleeplessness, depression.
Gastrointestinal- Nausea, vomiting, abdominal pain, constipation
Miscellaneous- Muscle pain, chest pain, swelling of tissues, skin rash, , protein in urine.
Musculoskeletal- Immune-mediated necrotizing myopathy.
Other Precautions : 
*Avoid changing dosage with out consulting health care providers.
*Monitor liver function, kidney function, and cholesterol level in blood regularly.
Storage Conditions : 
Store it at room temperature(20-25°C).
♦ Safety Labeling Changes Approved By FDA

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Posted by:  neelamrana, India  Posted on: 3/21/2013
Hi,I am 44 yrs old women and i have been prescribed rosuvas 20mg for my high cholesterol.I have been having it almost regularly for the past 2 years.Now i have started feeling tinnitus in my ears please i would like to know if this is some side effect of Rosuvas
Posted by:  jagdev, India  Posted on: 10/26/2012
hi i am 38 years old . i am using rozavel 10 for high cholestrol from last 4 month . now my cholestrol is normal in report but problem is that i am feeling muscular pain in both legs so weekness .. is this side effect of medicine rozavel 10 or any others ..
Posted by:  Manuj1988, India  Posted on: 9/14/2012
Hi my father is taking rosuvas 20 mg since past many months.doctars prescribed him to take pantop, telma 80, remilyn d, and rosuvas 20mg. His cholesterol level (LDL) is 140 . Doctor suggested him to undergo angiography test and arteries found to be normal . My father's blood pressure remains at 80/130 most of the time. The problem is that he is having serious problem of weakness in both leg and left arm. My father visited his doctor today and he suggested him to stop taking rosuvas 20 mg for 14 days and now asked him to have mecobal tablets.
sir I am very tensed about my papa's Heath. Please suggest me if these symptoms of weakness are because of side effects of medicines and something else like peripheral neuropathy .
Please I am waiting anxiously ...
Thank you ..
Posted by:  Adeeba, India  Posted on: 6/29/2012
Very informative. What problems can occur if discontinued after the Cholesterol level is brought down to normal? Is it habit forming? What are the dangers of continued usage? It would be helpful if these information are included.

Posted by:  SARKARAMMA, India  Posted on: 4/16/2012
I HAVE BEEN DIAGNIOSED FOR FATTY LIVER. Golby was administered to me for two months. I have high chlostrol now and is advised to take Rosuvas-F. I may kindly be advised whether consuming Rosuvas F will be harmful for liver.
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Reference  

  • Food and Drug Administration (FDA)
  • National Institutes of Health (NIH)
  • PubMed
  • CIMS
  • Indian Pharma Reference Guide 2012
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