Generic Name : Romiplostim Pronunciation : roe-mi-PLOE-stim Therapeutic Classification : Anticoagulants / Antithrombotics ICD Code : Y44.2
International- Nplate. Why it is prescribed (Indications) :
This medication is a thrombopoietin (TPO) mimetic protein, prescribed for low platelets (thrombocytopenia). It works by causing the cells in the bone marrow to produce more platelets. When it is not to be taken (Contraindications): Hypersensitivity and angioedema.
Dosage & When it is to be taken :
SC- The initial dose is 1 mcg/kg based on actual body weight. How it should be taken :
It comes as a powder (diluted with fluid) for injection, to be administered by a healthcare provider under the skin. Warnings and Precautions :
* Caution should be exercised in patients with history of kidney or liver impairment, bone marrow depression, blood cancer, (eg, myelodysplastic syndrome [MDS]), blood clotting or bleeding problems, heart attack, stroke, blood clots, who are taking other medications, any allergy, children, elderly, during pregnancy and breastfeeding.
* It may increase the risk of high platelet counts and blood clots; consult with your healthcare before taking this medication.
* Withdrawal of this medication may lead to increased risk of low platelet counts; avoid injury or bruising.
* It may cause dizziness, do not drive a car or operate machinery while taking this medication. Side Effects :
Dizziness, headache, indigestion, joint pain, muscle tenderness or weakness, shoulder pain, stomach pain or upset, and trouble in sleeping.
* Avoid excess dosage. Storage Conditions :
Store it in refrigerator (2° to 8°C). Do not freeze.
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