Medindia » Medication Manual » Romiplostim

Romiplostim

Updated on : November - 2012
Latest prescription information about Romiplostim. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
Email Email print Print Save this page Save Syndicate Syndicate
Generic Name : Romiplostim
Pronunciation : roe-mi-PLOE-stim
Therapeutic Classification : Anticoagulants / Antithrombotics
ICD Code : Y44.2
Trade Name(s): 
International- Nplate.
Why it is prescribed (Indications) : 
This medication is a thrombopoietin (TPO) mimetic protein, prescribed for low platelets (thrombocytopenia). It works by causing the cells in the bone marrow to produce more platelets.
When it is not to be taken (Contraindications): Hypersensitivity and angioedema.

Pregnancy Category :

A B C D X
Category C : Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

Dosage & When it is to be taken : 
SC- The initial dose is 1 mcg/kg based on actual body weight.
How it should be taken : 
It comes as a powder (diluted with fluid) for injection, to be administered by a healthcare provider under the skin.
Warnings and Precautions : 
* Caution should be exercised in patients with history of kidney or liver impairment, bone marrow depression, blood cancer, (eg, myelodysplastic syndrome [MDS]), blood clotting or bleeding problems, heart attack, stroke, blood clots, who are taking other medications, any allergy, children, elderly, during pregnancy and breastfeeding.
* It may increase the risk of high platelet counts and blood clots; consult with your healthcare before taking this medication.
* Withdrawal of this medication may lead to increased risk of low platelet counts; avoid injury or bruising.
* It may cause dizziness, do not drive a car or operate machinery while taking this medication.
Side Effects : 
Dizziness, headache, indigestion, joint pain, muscle tenderness or weakness, shoulder pain, stomach pain or upset, and trouble in sleeping.
Other Precautions : 
* Avoid excess dosage.
Storage Conditions : 
Store it in refrigerator (2° to 8°C). Do not freeze.

Comment & Contribute
Comments should be on the topic and should not be abusive. Comments are normally moderated and are reviewed after they are posted.
* Your comment can be maximum of 2500 characters
I agree to the terms and conditions
If you have a question about health related issues, you can now post it in our Ask An Expert section on our community website Medwonders.com and get answers from our panel of experts.

Browse the Drugs alphabetically

Reference  

  • Food and Drug Administration (FDA)
  • National Institutes of Health (NIH)
  • PubMed
  • CIMS
  • Indian Pharma Reference Guide 2012
Drugs Index
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z