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Riluzole

Latest prescription information about Riluzole. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
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Generic Name : Riluzole
Pronunciation : ril' yoo zole
Therapeutic Classification : Central Nervous System Agents
Trade Name(s): 
International- Rilutek.
Why it is prescribed (Indications) : 
This medication is a benzothiazole, recommended for amyotrophic lateral sclerosis (ALS, Lou Gehrig disease) is placed on a ventilator or breathing machine, by delaying onset of ventilator dependence or tracheostomy. It may prevent further damage to certain brain cells.
When it is not to be taken (Contraindications): Hypersensitivity.

Pregnancy Category :

A B C D X
Category C : Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

Dosage & When it is to be taken : 
The recommended dose is 50 mg orally every 12 hours.
How it should be taken : 
This medication available in the form of tablet to take by mouth, twice a day, every 12 hours.
Warnings and Precautions : 
*Caution should be exercised in patients with history of allergies, blood disorders or anemia or kidney or liver disease, pregnant, plan to become pregnant and breastfeeding.
*Cigarette smoking may decrease the effectiveness of this drug.
Side Effects : 
Central Nervous System- Dizziness, depression.
Gastrointestinal- Upset stomach, diarrhea, loss of appetite.
Miscellaneous- Tiredness, muscle weakness, difficulty in breathing, fever.
Other Precautions : 
*To avoid liver damage, do not drink alcoholic beverages.
Storage Conditions : 
Store at 25°C. Store it in an airtight container.


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Posted by:  milind123, India  Posted on: 8/14/2012
do this drug work in motor neuron disease patient?

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Reference  

  • Food and Drug Administration (FDA)
  • National Institutes of Health (NIH)
  • PubMed
  • CIMS
  • Indian Pharma Reference Guide 2012
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