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Generic Name : Rilpivirine
Pronunciation : RIL-pi-VIR-een
Therapeutic Classification : Antivirals
ICD Code : Y41.5
♦ Safety Labeling Changes Approved By FDA
Trade Name(s): International- Edurant. Why it is prescribed (Indications) : This medication is a second-generation non-nucleoside reverse transcriptase inhibitor (NNRTI), prescribed for HIV infection. It works by blocking the growth of HIV. When it is not to be taken (Contraindications): It should not be co-administered with anticonvulsants, antimycobacterials, proton pump inhibitors, glucocorticoids, and St John's wort.
Dosage & When it is to be taken : PO- The recommended dose is 25 mg once daily with a meal. How it should be taken : It comes as a tablet to take by mouth, with food. Warnings and Precautions : * Caution should be exercised in patients with history of kidney problems, irregular heartbeat, liver impairment, mental illness, suicidal thoughts, any allergy, who are taking other medications, elderly, children, during pregnancy and breastfeeding. * It may cause dizziness, do not drive a car or operate machinery while taking this medication. * It does not stop the spread of HIV to others; avoid sexual contact, sharing needles, injection supplies during the treatment period. * Accumulation or loss of body fat may occur in some body parts; if it is so consult with your healthcare provider. ♦*Patient may develop Immune Reconstitution Syndrome and Depressive Disorders such as depressed mood, depression, dysphoria, major depression, mood altered, negative thoughts, suicide attempt, suicidal ideation. Side Effects : Gastrointestinal - Nausea, abdominal pain, vomiting. General - Fatigue. Central Nervous System - Headache, dizziness, depression, sleeplessness, abnormal dreams. Skin – - Rash. * Avoid excess dosage. Storage Conditions : Store Rilpivirine between 59 and 86 degrees F (15 and 30 degrees C). Store in a tightly closed container away from heat, moisture, and light. |
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