Medindia » Medication Manual » Rilpivirine

Rilpivirine

Updated on : August - 2012
Latest prescription information about Rilpivirine. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
Email Email print Print Save this page Save Syndicate Syndicate
Generic Name : Rilpivirine
Pronunciation : RIL-pi-VIR-een
Therapeutic Classification : Antivirals
ICD Code : Y41.5
Trade Name(s): 
International- Edurant.
Why it is prescribed (Indications) : 
This medication is a second-generation non-nucleoside reverse transcriptase inhibitor (NNRTI), prescribed for HIV infection.  It works by blocking the growth of HIV.
When it is not to be taken (Contraindications): It should not be co-administered with anticonvulsants, antimycobacterials, proton pump inhibitors, glucocorticoids, and St John's wort.

Pregnancy Category :

A B C D X
Category B : Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.

Dosage & When it is to be taken : 
PO- The recommended dose is 25 mg once daily with a meal.
How it should be taken : 
It comes as a tablet to take by mouth, with food.
Warnings and Precautions : 
* Caution should be exercised in patients with history of kidney problems, irregular heartbeat, liver impairment, mental illness, suicidal thoughts, any allergy, who are taking other medications, elderly, children, during pregnancy and breastfeeding.
* It may cause dizziness, do not drive a car or operate machinery while taking this medication.
* It does not stop the spread of HIV to others; avoid sexual contact, sharing needles, injection supplies during the treatment period.
* Accumulation or loss of body fat may occur in some body parts; if it is so consult with your healthcare provider.
*Patient may develop Immune Reconstitution Syndrome and Depressive Disorders such as depressed mood, depression, dysphoria, major depression, mood altered, negative thoughts, suicide attempt, suicidal ideation.
Side Effects : 
Gastrointestinal - Nausea, abdominal pain, vomiting.
General - Fatigue.
Central Nervous System - Headache, dizziness, depression, sleeplessness, abnormal dreams.
Skin – - Rash.
Other Precautions : 
* Avoid excess dosage.
Storage Conditions : 
Store Rilpivirine between 59 and 86 degrees F (15 and 30 degrees C). Store in a tightly closed container away from heat, moisture, and light.
♦ Safety Labeling Changes Approved By FDA

Comment & Contribute
Comments should be on the topic and should not be abusive. Comments are normally moderated and are reviewed after they are posted.
* Your comment can be maximum of 2500 characters
I agree to the terms and conditions
If you have a question about health related issues, you can now post it in our Ask An Expert section on our community website Medwonders.com and get answers from our panel of experts.

Browse the Drugs alphabetically

Reference  

  • Food and Drug Administration (FDA)
  • National Institutes of Health (NIH)
  • PubMed
  • CIMS
  • Indian Pharma Reference Guide 2012
Drugs Index
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z