Why it is prescribed :
This medication is an antibiotic, prescribed for traveler's diarrhea caused by certain bacteria and liver disease affecting the brain (hepatic encephalopathy). It prevents the growth of bacteria inside the intestine (gut).
When it is not to be taken (Contraindications):
Category C :
Animal studies have shown adverse effects on the fetus and there are no appropriate studies in pregnant women, but potential benefits may allow the use of the drug in pregnant women despite the potential for risks.
Dosage & When it is to be taken (Indications):
Travelerís Diarrhea-It is administered orally in a dose of 600 mg in 3 divided doses for a 3-day course. For hepatic encephalopathy, it is administered as 1100 mg/day in 2 divided doses.
How it should be taken :
It comes as a tablet to take by mouth. It is usually taken with or without food three times a day for 3 days.
Warnings and Precautions :
Caution needed for pregnant and breastfeeding women, patients with history of severe liver disease,blood in stool, and any allergy.
It may cause dizziness, do not drive a car or operate machinery while taking this medication.
Side Effects :
Central Nervous System
Headache, abnormal dreams, dizziness, migraine, syncope, sleeplessness, fatigue.
Sunburn, clamminess, rash, increased sweating.
Eye and ENT
Ear pain, motion sickness, perception of sound within the human ear in the absence of corresponding external sound, nasal passage irritation, stuffy nose, runny nose.
Constipation, vomiting, abdominal distension, diarrhea, dry throat, fecal abnormality, gingival disorder, hernia, dry lips, stomach discomfort, dysentery, blood in stool, loss of appetite, loss of taste.
Blood in urine, bile salts in the urine, painful urination, urinary frequency, protein in urine.
Abnormal increase in the number of lymphocytes, monocytes, decrease in neutrophils.
Allergic reactions, rash, edema, hives, itching.
Weight loss, dehydration.
Joint pain, muscle spasms, muscle pain, neck pain.
Upper respiratory tract infection, difficulty in breathing.
Chest pain, uneasiness, weakness, hot flashes.
Other Precautions :
It may lead to dehydration, drink adequate liquid.
Storage Conditions :
Store it at room temperature, in an airtight container. Keep away from excess heat and moisture.