Regorafenib - Drug Information

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Generic Name : Regorafenib

Latest prescription information about Regorafenib. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.

Trade Names/Brand Names : 

International- Stivarga.

Why it is prescribed : 

This medication is a kinase inhibitor, prescribed for metastatic colorectal cancer (CRC) in patients who have been previously treated with fluoropyrimidine- oxaliplatin-and irinotecan-based chemotherapy. It works by helping to stop cancer cells from growing.

Pregnancy Category :


A B C D X

Category D :

There is an evidence of fetal risk based on adverse reaction data, but potential benefits may allow the drug to be used in pregnant women despite risks.

Dosage & When it is to be taken (Indications): 

PO- The recommended dose is 160mg, once daily for the first 21 days of each 28-day cycle.

How it should be taken : 

It comes as a tablet to take by mouth with food.

Warnings and Precautions : 

Caution should be exercised in patients with history of bleeding problems, high blood pressure, heart, liver, or kidney diseases, any allergy, who are taking other medications, during pregnancy and breastfeeding.
Avoid drinking grapefruit juice while taking this medication.
Patient may develop with increased risk of Reversible Posterior Leukoencephalopathy Syndrome (RPLS). If it is so consult with your doctor immediately.

Side Effects : 

  Most Common: Weakness, fatigue, decreased appetite and food intake, Hand-foot skin reaction (HFSR) (palmar-plantar erythrodysesthesia [PPE]), diarrhea, weight loss, and infection.
   General : Fever.
   Metabolic : Anemia, weight loss.
   Skin : Rash.
   Gastrointestinal : Diarrhea.
   Heart : High blood pressure, bleeding.
   Respiratory : Difficulty in breathing.


Other Precautions : 

Avoid excess dosage.

Storage Conditions : 

Store it at controlled room temperature (15 to 30C).


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arvindjava 

Dear All, Can anyone help me with the supply of Regorafenib,my father is a CRC patient

B.K.DEY 

Regorafenib [Stivarga] Drug Information is required. As this drug is not available in India. Can you let me Know which company is manufacturing or,Marketing this Drug in India. How to procure this drug for my friend on Prescription. My friend Dr Bharetendu Madeka , He is M.B.B.S Doctor himself suffering from Metastatic Colo rectal Cancer. Staying in Kolkata How can he get the medicine at a concessional rate and make the Drug easily available in Kolkata. Please Reply DR BIJAN KUMAR DEY. Email : deybijankumar@Yahoo.co.in

prem_gunjal 

Dear Sir/Madam, I am in reqiurement of the regerofeneb tablets in pune. can anyone help me in this concern.

shomallajan 

is regerofeneb available in india...if not how could I purchase it in india....

niftytrader 

regerofenib available asia. niftytrader@gmail.com

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