Generic Name : Raltegravir Pronunciation : ral-TEG-ra-vir Therapeutic Classification : Antivirals ICD Code : Y41.5♦ Safety Labeling Changes Approved By FDA
International- Isentress. Why it is prescribed (Indications) :
This medication is an antiretroviral agent, prescribed for HIV/AIDS. It blocks HIV-1 integrase, an enzyme needed for the HIV virus growth. When it is not to be taken (Contraindications):
Dosage & When it is to be taken :
Adult- Oral- The recommended dose is 400 mg, twice daily. How it should be taken :
It comes as a tablet to take by mouth, with or without food. Warnings and Precautions :
* Caution should be exercised in patients with history of liver problems or hepatitis B or C, muscle weakness, who are taking other medications, any allergy, elderly, children, during pregnancy and breastfeeding.
* It may cause dizziness, do not drive a car or operate machinery while taking this medication.
* Avoid stopping of this medication due to short supply. Store sufficient quantity.
* Avoid sexual intercourse during the treatment; otherwise infection may spread.
♦ *Patient may develop Immune Reconstitution Syndrome. Side Effects :
Most Common- Sleeplessness.
Gastrointestinal Disorders- Abdominal pain, stomach inflammation and nausea.
Liver- Liver inflammation.
Immune System- Hypersensitivity.
Central Nervous System- Dizziness, headache, weakness and fatigue.
Genitourinary- Kidney failure.
* Monitor complete blood counts regularly while taking this medication.
Storage Conditions :
Store it at room temperature (25°C), and in an airtight container. Keep away from children.
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