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Generic Name : Raltegravir
Pronunciation : ral-TEG-ra-vir
Therapeutic Classification : Antivirals
ICD Code : Y41.5
♦ Safety Labeling Changes Approved By FDA
Trade Name(s): International- Isentress. Why it is prescribed (Indications) : This medication is an antiretroviral agent, prescribed for HIV/AIDS. It blocks HIV-1 integrase, an enzyme needed for the HIV virus growth. When it is not to be taken (Contraindications): Hypersensitivity.
Dosage & When it is to be taken : Adult- Oral- The recommended dose is 400 mg, twice daily. How it should be taken : It comes as a tablet to take by mouth, with or without food. Warnings and Precautions : * Caution should be exercised in patients with history of liver problems or hepatitis B or C, muscle weakness, who are taking other medications, any allergy, elderly, children, during pregnancy and breastfeeding. * It may cause dizziness, do not drive a car or operate machinery while taking this medication. * Avoid stopping of this medication due to short supply. Store sufficient quantity. * Avoid sexual intercourse during the treatment; otherwise infection may spread. ♦ *Patient may develop Immune Reconstitution Syndrome. Side Effects : Most Common- Sleeplessness. Gastrointestinal Disorders- Abdominal pain, stomach inflammation and nausea. Liver- Liver inflammation. Immune System- Hypersensitivity. Central Nervous System- Dizziness, headache, weakness and fatigue. Genitourinary- Kidney failure. * Monitor complete blood counts regularly while taking this medication. Storage Conditions : Store it at room temperature (25°C), and in an airtight container. Keep away from children. |
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