Raloxifene - Drug Information

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General Information on Raloxifene

Generic Name : Raloxifene

Pronunciation : ral-OX-i-feen

Latest prescription information about Raloxifene. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
ICD Code : Y42.6 | Therapeutic Classification : Hormones

Trade Names/Brand Names of Raloxifene

Why is Raloxifene Prescribed? (Indications)

This medication is a selective estrogen receptor modulator (SERM) prescribed for treatment and prevention of osteoporosis in postmenopausal women. It is also used for reduction in risk of invasive breast cancer in postmenopausal women with osteoporosis and those at high risk for invasive breast cancer. It decreases bone turnover and increases bone density.  

When should Raloxifene not to be taken? (Contraindications)

Contraindicated in patients with allergy to the drug; active or past history of venous blood clot events including deep vein thrombosis, pulmonary embolism and retinal vein thrombosis, pregnancy, nursing mothers.

Pregnancy Category

A B C D X

Category X :

Animal and/or human studies have demonstrated fetal injury and potential risks outweigh the benefits of the drug in pregnancy. These drugs are found to be harmful when taken during pregnancy, and should not be used.

What is the dosage of Raloxifene?

Adult: PO- The recommended dose is 60 mg/day.

How should Raloxifene be taken?

It comes as a tablet to take by mouth. It is usually taken once a day with or without food.

What are the warnings and precautions for Raloxifene?

You should follow the diet and exercise recommended by the doctor regularly.
Calcium and Vitamin D should be taken if needed.
Monitor your body weight regularly to prevent bone weakness.
It may cause blood clots, so avoid sitting in one place.
It is not recommended for men.
Caution needed for pregnant women, elderly, and children, patients with history of heart failure, liver or kidney disease, excess in triglycerides in blood.

What are the side effects of Raloxifene?

  Serious adverse effects: Deep vein thrombosis (clotting in the deep veins), pulmonary embolus, stroke.
  Most Common: Hot flushes, leg cramps, sweating, sleep disorders, peripheral edema, vaginal bleeding; flu-like symptoms, rashes, headache.
  Gastrointestinal: Nausea, vomiting, diarrhea, GI disturbances.
  Metabolic: Weight gain.
  Musculoskeletal: Joint pain, muscle pain, inflammation of joints, tendon disorder.
  Central Nervous System: Depression, sleeplessness, dizziness, nerve disease.
  Respiratory: Inflammation of respiratory tract, runny nose, increased cough.
  Skin: Rash, sweating.
  Eye: Inflammation of conjunctiva.
  Genitourinary: Urinary tract infection, inflammation of vagina, vaginal bleeding, uterine disorder.
  Potentially Fatal: Endometrial carcinoma and thromboembolic events.

What are the other precautions for Raloxifene?

Take exactly as directed by your healthcare provider.

What are the storage conditions of Raloxifene?

Oral: Store at 15-30C.Keep this medication in an airtight container, and room temperature. Keep away from children.

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