Rabeprazole - Drug Information

Generic Name : Rabeprazole | Pronunciation : ra-BEP-ra-zole

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Latest prescription information about Rabeprazole. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
ICD Code : Y53.0 | Therapeutic Classification : Antiulcers
Drug Information

Trade Name(s): 

India : 


International : 


Why it is prescribed (Indications) : 

This medication is a proton pump inhibitor, prescribed for duodenal ulcer, gastro esophageal reflux disease (GERD), and Zollinger-Ellison (gastric acid hyper secretion) syndrome. It works by decreasing the amount of acid made in the stomach. 

When it is not to be taken (Contraindications): 

Concomitant administration of clarithromycin with pimozide and cisapride is contraindicated.
Contraindicated in patients with known hypersensitivity.

Pregnancy Category :






Category B :

Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.

Dosage & When it is to be taken : 

PO- Gastro-oesophageal reflux disease; erosive oesophagitis: 20 mg once daily in the morning for 4-8 weeks. Maintenance: 10-20 mg once daily.
For non-erosive oesophagitis: 10 mg once daily for 4 wk, upon symptom resolution, may continue with 10 mg once daily when needed.
Healing of Duodenal Ulcers: 20 mg/day after the morning meal for 4 weeks; additional therapy may be required for some patients.
Zollinger-Ellison: 60 mg once daily. Adjust according to patient’s needs.

How it should be taken : 

It comes as a delayed-release (long-acting) tablet to take by mouth. It is usually taken once a day for 4 to 8 weeks, but it is sometimes taken for a longer time, with or without food.

Warnings and Precautions : 

Caution should be exercised in patients with history of bleeding ulcer, such as black, tarry stools or vomit that looks like coffee grounds, or if you experience throat pain, chest pain, severe stomach pain, or trouble swallowing contact your doctor immediately.
May increase the risk of GI infections due to acid suppressive effects, liver damage, gastric tumor.

Side Effects : 

  Central Nervous System
- Headache, dizziness, disorientation/delirium.

- Skin eruptions, severe allergic reactions.

  Eye and ENT
- Inflammation of pharynx.

- Diarrhea, nausea, abdominal pain, vomiting, flatulence, constipation, abdominal pain, dry mouth.

- Kidney disorder.

- Occurrence of confusion, altered level of consciousness and coma as a result of liver failure (hepatic encephalopathy), inflammation of liver, increased liver enzymes, jaundice.

- Decrease in white blood cells, anemia.

- Excess ammonia in blood, thyroid stimulating hormone elevations.

- Joint pain, muscle pain, rapid breakdown of skeletal muscle.

- Inflammation of lung tissue.

- Pain, infection, rapid swelling of dermis, coma, sudden death.

Other Precautions : 

Avoid abrupt withdrawal.

Storage Conditions : 

Oral: Store at 15-30°C. Store it in an airtight container and keep away from children.


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Sir, Earlier I had some gastric problems and I take antacids for the same. Recently I am experiencing heavy gastric problems, ie i feel difficulty in breathing, my nose blocking. if i take some hot water it will be released in few minutes but till such time i had to suffer a lot. if suppose i am outside my thinking would be what would happen to me and naturally the fear comes and sweat a lot. i had done the endoscopy, scan and other thing, they say that its not a gerd. Nowadays i am gettting it frequently before every meal. At this time if i intake something it will be ok. I would like to know whtr is it the problem of piles or something related to the anus, I used to discharge gas through anus, but sometimes it stops and at this time I am experiencing this problem for a longer time say 30mts to 1 hour. One of my freind told me to take veloz 20mg. Is it adivisable. after food nothing will be there for the next 2 or 3 hours, then again it starts. First thing is very difficult in breathing and nose got blocked. once it is cleared everything will be ok. Please suggest the remedy for this. regards dinesh
dinesh1607  Sunday, May 3, 2015
Please give me a suggestion ,,,i am taking Rablet 20 along with etoshine and Peg SR 75 mg and Mythyloco for neck pain...Is it ok or can I take for 10 days?
Hedayetullah  Saturday, March 21, 2015
I would like to know the effects of taking rabeloc with alcohol
winield  Tuesday, July 1, 2014
Hi, I have been taking RCLonac for the pains atleast two in a week, will this effect my health, i faced ulcers when i was taking Eterobax-60mg. What would be the results if i take RClonac for long time? and any alternative medicine available? I met a very good doctors so far. please suggest. I feel huge pains in joints and other places in my body occationally and my body has deficiency of Vit-D and B12 long back and i could cover them, but no change in pains, i have been suffering with these pains since 15 years.
vijay27  Friday, October 4, 2013
Hi, I have been taking Creon 10K since a year for pancreatic prolem. My doctor suggest that Rabeloc 20 for 1 tab can be taken in daily with empty stomech. Can you please advise me why the drug prescribed to me along with Creon 10K
Tomas  Monday, June 18, 2012
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