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Medindia » Medication Manual » Quinapril

Quinapril

Updated on : September - 2012

Latest prescription information about Quinapril. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.

Generic Name : Quinapril

Pronunciation : KWIN-a-pril

Therapeutic Classification : ACE Inhibitors

ICD Code : Y52.4

Trade Name(s):
India- Acupil, Q-Pril, Q Press.
International- Accupril.

Why it is prescribed (Indications) :
This medication is an angiotensin-converting enzyme (ACE) inhibitor, prescribed for high blood pressure and heart failure either alone or with other medications. It works by relaxing blood vessels.

When it is not to be taken (Contraindications): Contraindicated in patients with angioedema, and known hypersensitivity.

Pregnancy Category :

A B C D X

Category D : There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

Dosage & When it is to be taken :
Adult- PO- Hypertension: The recommended initial dose is 10 or 20 mg once daily. It may be adjusted if needed.
Congestive Heart Failure: Initial dose: 5 mg orally twice a day. Maintenance: 10-20 mg orally twice a day.

How it should be taken :
It comes as a tablet to take by mouth, on an empty stomach at least 1 hour before or 2 hours after food.

Warnings and Precautions :
* Caution should be exercised in patients with history of sugar, heart disease, blood vessel problems, poor blood circulation, bone marrow depression, kidney or liver impairment, stroke, recent heart attack, kidney transplant, autoimmune disease, dehydration, changes in blood minerals, any allergy, who are taking other medications, during pregnancy and breastfeeding.
* It may cause dizziness, lightheadedness, or fainting, do not drive a car or operate machinery while taking this medication.
* Avoid alcohol consumption.
* It may cause a serious side effect called angioedema (life-threatening allegic reactions) with swelling of the hands, face, lips, eyes, throat, or tongue; difficulty in swallowing or breathing; or hoarseness. If it is so consult with your doctor.
* Avoid exposure to sunlight; otherwise it may cause sunburn easily.
* Avoid contact with people who have infections.
* Monitor blood pressure, blood electrolyte levels, heart function, blood sugar, kidney or liver function regularly while taking this medication.

Side Effects :
Most Common - Dizziness, coughing, fatigue, nausea , vomiting, chest pain, low blood pressure, difficulty in breathing, diarrhea, headache, muscle pain, rash and back pain.
General - Uneasiness, viral infections and anaphylactoid reaction.
Heart - Palpitations, dilatation of blood vessels, fast heart rate, heart failure, heart attack, stroke, chest pain, high blood pressure, low blood pressure and abnormal heart rhythm.
Blood - Anemia.
Gastrointestinal - Flatulence, dry mouth or throat, constipation, gastrointestinal bleeding, inflammation of pancreas, abnormal liver function, and indigestion.
Central Nervous System - Drowsiness, fainting, nervousness, depression, sleeplessness, and tingling.
Skin - Hair loss, increased sweating, itching, skin inflammation, sensitivity to light, and rash.
Genitourinary - Urinary tract infection, impotence, and kidney failure.
Respiratory - Eosinophila and lung infection.
Miscellaneous - Abnormal vision, fluid retention, joint pain, liver inflammation, and decrease in platelets.

Other Precautions :
* Avoid excess dosage.

Storage Conditions :
Store it at controlled room temperature (15ï¿½ï¿½30ï¿½C).