Generic Name : Protamine Sulphate Pronunciation : PRO-tuh-meen SULL-fate Therapeutic Classification : Heparin Antagonists
India- Prothiobin, Prota, Neutrahep, Neoprota, Newtain.
International- Protamine Sulfate. Why it is prescribed (Indications) :
This medication is a heparin antagonist, prescribed for reversing the anticoagulant effects of heparin. When it is not to be taken (Contraindications):
Dosage & When it is to be taken :
IV- 1 mg for each 90 units of heparin derived from lung tissue or 115 units of heparin derived from intestinal mucosa. How it should be taken :
It comes as a solution for injection to be administered by a healthcare provider into the vein. Warnings and Precautions :
* Caution should be exercised in patients with history of poor blood circulation, heparin rebound, lung swelling, any allergy, children, during pregnancy and breastfeeding.
* Avoid too much rapid application.
* Monitor prothrombin time regularly while taking this medication. Side Effects :
Heart - Low blood pressure, slow heart rate, and circulatory collapse.
Central Nervous System - Lassitude.
Gastrointestinal - Nausea and vomiting.
Respiratory - Shortness of breath, lung swelling and acute pulmonary hypertension.
Miscellaneous - Severe respiratory distress, poor blood circulation, noncardiogenic lung swelling; transient flushing and feeling of warmth and back pain.
* Avoid excess dosage. Storage Conditions :
Store it at controlled room temperature (15 and 30°C). Do not freeze.
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