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Generic Name : Protamine Sulphate
Pronunciation : PRO-tuh-meen SULL-fate
Therapeutic Classification : Heparin Antagonists
Trade Name(s): India- Prothiobin, Prota, Neutrahep, Neoprota, Newtain. International- Protamine Sulfate. Why it is prescribed (Indications) : This medication is a heparin antagonist, prescribed for reversing the anticoagulant effects of heparin. When it is not to be taken (Contraindications): Hypersensitivity.
Dosage & When it is to be taken : IV- 1 mg for each 90 units of heparin derived from lung tissue or 115 units of heparin derived from intestinal mucosa. How it should be taken : It comes as a solution for injection to be administered by a healthcare provider into the vein. Warnings and Precautions : * Caution should be exercised in patients with history of poor blood circulation, heparin rebound, lung swelling, any allergy, children, during pregnancy and breastfeeding. * Avoid too much rapid application. * Monitor prothrombin time regularly while taking this medication. Side Effects : Heart - Low blood pressure, slow heart rate, and circulatory collapse. Central Nervous System - Lassitude. Gastrointestinal - Nausea and vomiting. Respiratory - Shortness of breath, lung swelling and acute pulmonary hypertension. Miscellaneous - Severe respiratory distress, poor blood circulation, noncardiogenic lung swelling; transient flushing and feeling of warmth and back pain. * Avoid excess dosage. Storage Conditions : Store it at controlled room temperature (15 and 30°C). Do not freeze. |
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