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Generic Name : Propylthiouracil
Pronunciation : proe pill thye oh yoor' a sill
Therapeutic Classification : Thyroid and Antithyroid Agents
ICD Code : Y42.2
Trade Name(s): International- PTU. Why it is prescribed (Indications) : This medication is an antithyroid agent, prescribed for hyperthyroidism. It stops the thyroid gland from making thyroid hormone. When it is not to be taken (Contraindications): Hypersensitivity.
Dosage & When it is to be taken : Adult: PO- 150-450 mg/day in divided doses. Severe: Initial: 600-1,200 mg/day. Maintenance for euthyroid patients: 50-150 mg/day. How it should be taken : It comes as a tablet to take by mouth, with food. Warnings and Precautions : * Caution should be exercised in patients with history of bone marrow depression; or liver disease, any allergy, who are taking other medications, during pregnancy and breastfeeding. * It may cause drowsiness or dizziness, do not drive a car or operate machinery while taking this medication. * Patient may develop with increased risk of liver damage and bone marrow depression; if it is so consult with your doctor. * It may affect platelet counts; avoid bruising or injury. Side Effects : Decrease in white blood cells and platelets, lupus-like syndrome, vein inflammation, skin rash, hives, joint pain, fever, GI discomfort, vomiting and headache. * Avoid excess dosage. Storage Conditions : Store it at room temperature. |
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