Propylthiouracil - Drug Information

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General Information on Propylthiouracil

Generic Name : Propylthiouracil

Pronunciation : proe pill thye oh yoor' a sill

Latest prescription information about Propylthiouracil. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
ICD Code : Y42.2 | Therapeutic Classification : Thyroid and Antithyroid Agents

Trade Names/Brand Names of Propylthiouracil

India : 

International : 

PTU

Why is Propylthiouracil Prescribed? (Indications)

This medication is an antithyroid agent, prescribed for hyperthyroidism. It stops the thyroid gland from making thyroid hormone.

When should Propylthiouracil not to be taken? (Contraindications)

Hypersensitivity.

Pregnancy Category

A B C D X

Category D :

There is an evidence of fetal risk based on adverse reaction data, but potential benefits may allow the drug to be used in pregnant women despite risks.

What is the dosage of Propylthiouracil?

Adult: PO- 150-450 mg/day in divided doses. Severe: Initial: 600-1,200 mg/day. Maintenance for euthyroid patients: 50-150 mg/day.

How should Propylthiouracil be taken?

It comes as a tablet to take by mouth, with food.

What are the warnings and precautions for Propylthiouracil?

Caution should be exercised in patients with history of bone marrow depression; or liver disease, any allergy, who are taking other medications, during pregnancy and breastfeeding.
It may cause drowsiness or dizziness, do not drive a car or operate machinery while taking this medication.
Patient may develop with increased risk of liver damage and bone marrow depression; if it is so consult with your doctor.
It may affect platelet counts; avoid bruising or injury.

What are the side effects of Propylthiouracil?

Decrease in white blood cells and platelets, lupus-like syndrome, vein inflammation, skin rash, hives, joint pain, fever, GI discomfort, vomiting and headache.

What are the other precautions for Propylthiouracil?

Avoid excess dosage.

What are the storage conditions of Propylthiouracil?

Store it at room temperature.

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