Generic Name : Propylthiouracil Pronunciation : proe pill thye oh yoor' a sill Therapeutic Classification : Thyroid and Antithyroid Agents ICD Code : Y42.2
International- PTU. Why it is prescribed (Indications) :
This medication is an antithyroid agent, prescribed for hyperthyroidism. It stops the thyroid gland from making thyroid hormone. When it is not to be taken (Contraindications): Hypersensitivity.
Dosage & When it is to be taken :
Adult: PO- 150-450 mg/day in divided doses. Severe: Initial: 600-1,200 mg/day. Maintenance for euthyroid patients: 50-150 mg/day. How it should be taken :
It comes as a tablet to take by mouth, with food. Warnings and Precautions :
* Caution should be exercised in patients with history of bone marrow depression; or liver disease, any allergy, who are taking other medications, during pregnancy and breastfeeding.
* It may cause drowsiness or dizziness, do not drive a car or operate machinery while taking this medication.
* Patient may develop with increased risk of liver damage and bone marrow depression; if it is so consult with your doctor.
* It may affect platelet counts; avoid bruising or injury. Side Effects :
Decrease in white blood cells and platelets, lupus-like syndrome, vein inflammation, skin rash, hives, joint pain, fever, GI discomfort, vomiting and headache.
* Avoid excess dosage. Storage Conditions :
Store it at room temperature.
Comment & Contribute
Ask an Expert