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Propofol

Latest prescription information about Propofol. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
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Generic Name : Propofol
Pronunciation : PROE-poe-fol
Trade Name(s): 
India- Celofol, Celofol (20 ml), Critifol, Critifol (50 ml), Diprivan, Fresofol, Fresofol (50 ml), Neorof, Propovan (20 ml), Rofol, Hypro.
International- Diprivan.
Why it is prescribed (Indications) : 
This medication is a general anesthetic, prescribed for induction and maintenance of general anaesthesia.

When it is not to be taken (Contraindications): 


Contraindicated in patients with allergies to eggs, egg products, soybeans or soy products, and hypersensitivity.

Pregnancy Category :

A B C D X
Category B : Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.


When it is to be taken : 
Adult- Induction: 40 mg by inj or infusion every 10 sec. Usual dose: 1.5-2.5 mg/kg. Maintenance: 4-12 mg/kg/hour or intermittent bolus inj of 20-50 mg.
Child- >8 year: Induction dose of 2.5 mg/kg. Maintenance dose: 9-15 mg/kg/hour by IV infusion or intermittent bolus inj.
Elderly- Including neurosurgical and debilitated patients: Infuse at a rate of 20 mg every 10 sec. Maintenance: 3-6 mg/kg/hour. Usual dose needed: 1-1.5 mg/kg.
How it should be taken : 
It comes as a solution for injection to be administered by a healthcare provider into the vein.
Special Instruction : 
*It may decrease mental alertness for some time after use. This effect may be worse if you drink alcohol or take certain medicines.
*Do not use it in newborns or infants. It may cause serious and sometimes fatal nervous system problems and other side effects.
*It should not be used to start anesthesia in children younger than 3 years old.
Side Effects : 
Central Nervous System- Involuntary muscle movements.
Gastrointestinal- Nausea, vomiting.
Miscellaneous- Headache, fever; pain, burning or stinging at injection site.
Other Precautions : 
*Monitor the signs of low blood pressure regularly.
Storage Conditions : 
It is normally handled and stored by healthcare providers.

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