Generic Name : Prochlorperazine Pronunciation : proe klor per' a zeen Therapeutic Classification : Antiemetics ICD Code : Y43.0
India- Bemetil, Bukatel, Comptil, Emex, Emidoxyn, Emidoxyn F, Emikind, Ingametil, Meditil-5, Mizeco, Motion Lu, Nausetil, Nuroflow, Setil, Stemetil, Vertex, Vestil-5, Vomclor, Vometil.
International- Compro, Procomp. Why it is prescribed (Indications) :
This medication is a tranquilizer, prescribed for schizophrenia, severe nausea and vomiting. When it is not to be taken (Contraindications):
Contraindicated in patients with CNS depression, children less than 2 years old, and hypersensitivity.
Dosage & When it is to be taken :
Nausea and Vomiting - Oral Dosage: Tablets: Take one 5 mg or 10 mg tablet 3 or 4 times daily.
Rectal Dosage: 25 mg twice daily.
I.M. Dosage: Initially 5 to 10 mg (1 to 2 mL) injected deeply.
Adult Psychiatric Disorders- Oral Dosage: The recommended dosage is 5 mg 3 or 4 times daily. How it should be taken :
It comes as a tablet, capsule, liquid to take by mouth, with or without food.
It also comes as a solution for injection to be administered by a healthcare provider into the vein or muscle.
It also comes as rectal suppositories, to insert through the rectum. Warnings and Precautions :
* Caution should be exercised in patients with history of heart disease, central nervous system depression, liver problems, low blood pressure, increased eye pressure, neuroleptic malignant syndrome, tardive dyskinesia, bone marrow depression, involuntary muscle movements, Parkinson disease, Reye syndrome, prostate enlargement, seizures, alcoholism, any allergy, who are taking other medications, elderly, children, during pregnancy and breastfeeding.
* It may cause drowsiness, dizziness, blurred vision or lightheadedness, do not drive a car or operate machinery while taking this medication.
* Avoid alcohol consumption.
* Avoid exposure sunlight. Side Effects :
Most Common - Drowsiness, dizziness, absence of menstrual periods, blurred vision, skin reactions and Neuroleptic Malignant Syndrome (NMS).
Gastrointestinal - Nausea, constipation and bowel obstruction.
Genitourinary - Ejaculatory disorders/impotence, painful erection, lazy colon, urinary retention, menstrual irregularities and false-positive pregnancy tests.
Heart - Low blood pressure and heart arrest.
Blood - Blood dyscrasias.
Liver - Jaundice and liver damage.
Metabolic - Increased appetite and increased weight.
* Avoid excess dosage. Storage Conditions :
Store it at controlled room temperature (15° and 30°C).
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