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Probenecid

Latest prescription information about Probenecid. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
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Generic Name : Probenecid
Pronunciation : proe ben' e sid
Therapeutic Classification : anti- gout medications
Trade Name(s): 
India- Benecid.
International- Benemid.
Why it is prescribed (Indications) : 
This medication is a uricosuric agent, prescribed for chronic gout and gouty arthritis.

When it is not to be taken (Contraindications): 


Contraindicated in children under 2 years of age, persons with known blood dyscrasias, kidney stone, hypersensitivity, during pregnancy and breastfeeding.

Pregnancy Category :

A B C D X
Category C : Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.


When it is to be taken : 
PO- The usual adult dose for hyperuricemia is 500 mg twice daily and the maximum dose is 2 grams daily.
How it should be taken : 
It comes as a tablet to take by mouth, with food.
Special Instruction : 
* Caution should be exercised in patients with history of ulcers, kidney stones,kidney disorder, blood disorder, any allergy, who are taking other medications, during pregnancy and breastfeeding.
* It may cause dizziness, do not drive a car or operate machinery while taking this medication.
* It may affect blood sugar level, monitor sugar level regularly.
Side Effects : 
Central Nervous System - Headache and dizziness.
Metabolic - Precipitation of acute gouty arthritis.
Gastrointestinal - Liver damage, vomiting, nausea, loss of appetite and sore gums.
Genitourinary - Kidney damage, blood in urine, kidney stone, back pain and urinary frequency.
Hypersensitivity - Shock, fever, hives and itching.
Blood - Anemia and decrease in white blood cells.
Skin - Skin inflammation, hair loss and flushing.
Other Precautions : 
* Drink adequate fluid especially during the first few months of treatment.
Storage Conditions : 
Store it at room temperature (20°-25°C).

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