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Pregabalin

Latest prescription information about Pregabalin. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
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Generic Name : Pregabalin
Pronunciation : pre gab' a lin
Therapeutic Classification : Anticonvulsants
ICD Code : Y46.6
Trade Name(s): 
India- Alnacob-P Cap, Capin Plus Cap, Cobal-Pg Cap, Doloneuron-Pg Cap, Ecogab Tab, Gabafit Cap, Gabafix M Cap, Gabanext Cap, Gaba-Pm Cap, Galinerve Cap, Lyrica Cap, Mahagaba-M Film-Coated Tab, Maxgalin Cap, Maxgalin-M Cap, Mecobion-P Cap, Mygalin Cap, Nervonic-P Tab, Neugaba Cap, Neupreg Cap, Neupreg Forte Cap, Neurica-M 150 Cap, Neurica-M 75 Cap, Neutron-Od Cap, Nuramed Cap, Pevesca Cap, Polam 150 Cap, Polam 75 Cap, Precob Tab, Preg Tab, Pregab Cap, Pregaba Cap, Pregaba Plus Cap, Pregaba-M Cap, Pregabid Cap, Pregabin Plus 150 Tab, Pregabin Plus 75 Tab, Pregabin Tab, Pregacon Cap, Pregalin Caps Cap, Preganerv-M Cap, Pregaric Cap, Pregaric-Plus Cap, Pregastar Cap, Pregeb Cap, Pregeb-M Cap, Preglan Inj, Preglan Tab, Preneu Tab, Preneu-M Tab, Proage Cap, Proage M Cap, Saneuron Cap, Saneuron-M Cap, Scogaba-M Cap, Zylin Cap.
International- Lyrica.
Why it is prescribed (Indications) : 
This medication is an anticonvulsant and neuropathic pain agent, prescribed for partial seizures; management of postherpetic neuralgia (nerve pain caused by the varicella zoster virus); management of fibromyalgia (a condition where the patient has muscle and connective tissue pain).  
When it is not to be taken (Contraindications): Hypersensitivity.

Pregnancy Category :

A B C D X
Category C : Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

Dosage & When it is to be taken : 
PO- Postherpetic neuralgia: Initial-150 mg/day in divided doses. Usual: 150-300 mg/day in divided doses. Max: 600 mg/day in divided doses.
Adjunct in partial seizures: 150-600 mg/day in divided doses. Max: 600 mg/day.
Fibromyalgia: Initial- 150 mg/day, up to 300 mg/day after 1 week if needed and then 450 mg/day if still needed.
Anxiety: Initial-150 mg/day. Increase slowly if needed. Max: 600 mg/day.
How it should be taken : 
It comes as a capsule to take by mouth. It is usually taken with or without food two or three times a day.
Warnings and Precautions : 
* Discontinue treatment if patients develop severe allergic reaction.
*Withdraw treatment gradually over at least 1 week.
*May cause peripheral edema.
*Regular vision check is recommended.
*May decrease platelet count and prolong PR interval.
*Mental health may change in unexpected ways and you may become suicidal (thinking about harming or killing yourself or planning or trying to do so) while you are taking this medication for the treatment of epilepsy.
Side Effects : 
Central Nervous System- Dizziness, sleepiness, fatigue, euphoric mood, confusion, irritability, shaky movements and unsteady walk (ataxia,tremor, abnormal coordination, problems with speech, memory or attention.
Eye and ENT- Blurred vision, double vision, abnormal vision, eye disorder, inflammation of conjunctiva, involuntary eye movement, inflammation of the middle ear, tinnitus.
Gastrointestinal- Dry mouth, constipation, increased appetite, flatulence, vomiting, abdominal distension, abdominal pain, gastroenteritis, diarrhea, nausea.
Genitourinary- Urinary incontinence, sexual dysfunction, impotence, libido decreased, urinary frequency.
Metabolic- Peripheral edema, weight gain, edema, face edema, low blood sugar.
Musculoskeletal- Joint pain, back pain, muscle spasm, leg cramps, myasthenia.
Respiratory-Sinusitis, inflammation of bronchus, difficulty in breathing.
Miscellaneous- Infection, pain, chest pain, flu syndrome, allergic reaction, easy bruising, fever, itching, hypersensitivity.
Other Precautions : 
*Avoid alcohol consumption while taking this medication.
Storage Conditions : 
Oral: Store at 25°C. Store it at room temperature and keep in an airtight container.

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Pregabalin Proves Durable Pain Relief Option for Fibromyalgia

Pregabalin, typically used to treat nerve pain or seizures, appears to offer extended pain relief for those with fibromyalgia, according to research presented this week at the American College of ...

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Posted by:  Drmohammedaijaz, United States  Posted on: 9/20/2011
This drugs have these many side effect so wt s d need to take for a single and simple disease

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Reference  

  • Food and Drug Administration (FDA)
  • National Institutes of Health (NIH)
  • PubMed
  • CIMS
  • Indian Pharma Reference Guide 2012
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